Reduced glutathione (GSH) and Glutathione S-transferase (GST) play important roles in the detoxification of several xenobiotic compounds, including pesticides. This study was carried out to access the effect of the organophosphate pesticide, dichlorvos on the activities of GSH, GST as well as lipid peroxidation of egg laying hens. Seven weeks old pullets weighing between 400-600 g divided into ...

In 2021, this study has attempted to analyze the trend of pesticide import over two decades in Nepal. Secondary data obtained from Plant Quarantine and Pesticide Management Center were analyzed know trend. The result showed that pesticides was increasing average annual increase 30.48 tons (a.i.) last twenty-two years. Fungicide had highest followed by insecticide, herbicide these three groups c...

Pesticides, such as parathion, are metabolized by cytochrome p-450 system to paraoxon, which is a potent cholinesterase inhibitor. Paraoxonase (PON) catalyzes the hydrolysis of these toxic metabolites and protects against pesticide toxicity. A glutamine/arginine (Gln/Arg) polymorphism at amino acid position 192 of PON has been described. The Arg/Arg genotype is associated with higher serum para...

Information on the health impacts of pesticides is quite limited in many developing countries, with many surveys relying solely on farmer self-assessments of their health status. To test the reliability of self-reported data, an acetyl cholinesterase enzyme (AChE) blood test was conducted for 190 rice farmers in the Mekong Delta, Vietnam. Results reveal a high prevalence of pesticide poisoning ...

BACKGROUND We recently reported a link between use of the organophosphate pesticide phorate and risk of prostate cancer among applicators with a family history of prostate cancer in the Agricultural Health Study (AHS). OBJECTIVE This finding, together with findings of associations between other organophosphate pesticides and cancer more broadly, prompted us to examine phorate exposure and ove...