Retinoids, also known as vitamin A, are non-endogenous molecules that essential for a number of physiological processes in mammals. Imbalance retinoids has been associated with reproductive impairment, embryonic mortality, growth retardation and bone deformities, pathologies skin the nervous system, immune suppression. Mammals cannot produce so their primary source is dietary. They absorbed by ...

The organochlorine compounds (OCs) contamination was studied in different tissues of the adult Black Sea turbot (BST) from natural spawning populations of 2008, 2009 and 2013 in the South-Western shelf off Crimea, the Black Sea. Total lipids, six congeners of polychlorinated biphenyl (CB 28, 52, 101, 138, 153, 180) and organochlorine pesticide p,p’DDT including its metabolites p,p’DDE and p,p’D...

Concentrations of organochlorine pesticides (DDTs, HCHs, and chlordanes), polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs), polycyclic aromatic hydrocarbons (PAHs), perfluorinated compounds (PFCs), and 20 trace elements were determined in livers of 3- to 5-year old stranded sea otters collected from the coastal waters of California, Washington, and Alaska (USA) and from ...

Remote coastal populations that rely on seafood for subsistence often receive unusually high doses of organochlorines and methyl mercury. Immunosuppression resulting from prenatal exposure to organochlorines has been reported in wildlife species and humans. In this study, we assessed lymphocyte activation and associated cytokine secretion in 47 newborns from a remote maritime population living ...

Organochlorine compounds, particularly polychlorinated biphenyls (PCBs), alter serum thyroid hormone levels in humans. Hydroxylated organochlorines have relatively high affinities for the serum transport protein transthyretin, but the ability of these compounds to interact with the human thyroid receptor is unknown. Using a baculovirus expression system in insect cells (Sf9 cells), we produced ...