The first electrophilic α-amination reaction of labdane-type diterpene (−)-(5S,9S,10S,13S)-labd-7-en-15-oic acid and (+)-(5S,8R,9R,10S,13R)-8-hydroxylabdan-15-oic acid, isolated from aerial parts Ageratina jocotepecana is presented. In the presence dibenzylazodicarboxylate proline followed by an in situ reduction, corresponding hydrazino alcohols were obtained. It demonstrated that moiety had n...

Self-assembling minimalistic peptides embedded with an organocatalytic moiety were designed. By controlling the formation of fibrils via external intervention, it was shown that activation is accelerated when organocatalyst in its supramolecular state. The effect catalysis demonstrated a Michael benchmark reaction.