OBJECTIVES To determine whether GPs should advise their older patients with chronic knee pain to use topical or oral non-steroidal anti-inflammatory drugs (NSAIDs). DESIGN An equivalence study was designed to compare the effect of advice to use preferentially oral or topical ibuprofen (an NSAID) on knee pain and disability, NSAID-related adverse effects and NHS/societal costs, using a randomi...

OBJECTIVES To know the nature, incidence and severity of oral manifestations occurring in postmenopausal women. STUDY DESIGN Oral changes were observed in 365 postmenopausal women and 365 age matched male individuals attending the department of Oral Medicine and Radiology. The patients were asked about complaints of dry mouth, taste and breath changes, mucosal and facial pain and were examine...

Background and Aim: Temporomandibular disorders (TMDs) can be associated with pain in other areas such as the neck. Multiple causes have been suggested for TMDs; parafunctional habits such as bruxism and clenching are among the most commonly suggested etiologies. This study aimed to assess the efficacy of the amendment of oral parafunctional habits in the improvement of TMDs and neck pain. M...

BACKGROUND The current investigation examined the determinants of oral health experiences associated with dentine hypersensitivity using prospective diary methodology. METHODS Staff and students from a large UK university who had self-diagnosed dentine hypersensitivity completed an online daily diary and text survey for 2 weeks recording their mood, oral health-related coping behaviours, copi...

recurrent aphthous stomatitis (ras) is the most common and painful oral inflammatory lesion with an unknown etiology. this study aims to determine the therapeutic effects of ibuprofen, diphenhydramine and aluminum magnesium simethicone (almgs) syrup on reducing oral aphthous ulcer pain.thirty-one patients with ras participated in this double-blind clinical trial. subjects were randomly divided ...

Cancer pain is highly prevalent and often severe. Fortunately, most cancer pain can be readily managed, with up to 90% of patients responding well to standard interventions. However, breakthrough cancer pain-brief flares of severe pain superimposed on baseline pain-is common, difficult to manage, and often negatively impacts patients' quality of life. Breakthrough cancer pain is traditionally m...

Objective: The present study was designed to investigate the analgesic effect of oral and i.p. administration of alcoholic Viscum album (V.A) fruit extract as a rich source of alkaloid substances. Materials and Methods: Experimented animals were divided into control and treatment groups. The treatment rats received different doses of the V.A fruit extract, which was prepared from alcoholic sma...

background and aims: although laparoscopy itself is a new step to improve the quality of different types of surgery, reducing their complications postoperative pain remains a major problem. this study compares the effects of low dose oral gabapentin with placebo to control postoperative pain in patients undergoing laparoscopic cholecystectomy . materials and methods: in this double-blind random...

conclusions we conclude that volume of residual pneumoperitoneum is a contributing factor in the etiology of postoperative pain after laparoscopic cholecystectomy. results at the end of the study, 17 patients (30.9%) had no residual pneumoperitoneum after 24 hours; which 23 (41.81%) had mild residual pneumoperitoneum, eight (14.54%) had moderate pneumoperitoneum and seven (12.72%) had severe pn...