It has not been verified whether allopurinol application is beneficial in decreasing the severity of radiation-induced oral mucositis and dermatitis. Rats were divided into 4 groups and received 15 Gy irradiation on the left whisker pad. Group 1 received only irradiation. Group 2 was maintained by applying allopurinol/carrageenan-mixed gel (allopurinol gel) continuously from 2 days before to 20...

Objective. To raise awareness of plasma cell mucositis as a rare differential diagnosis for oral mucosal ulceration and its macroscopic similarity to malignancy. Method. We report a patient who presented with oral features suggestive of malignancy. A biopsy revealed plasma cell mucositis. Results. The patient successfully had a full excision of one lesion and a spontaneous resolution of the oth...

PURPOSE We conducted a clinical study to correlate oral cavity dose with clinical mucositis, perform in vivo dosimetry, and determine the feasibility of obtaining buccal mucosal cell samples in patients undergoing head-and-neck radiation therapy. The main objective is to establish a quantitative dose response for clinical oral mucositis. METHODS AND MATERIALS Twelve patients undergoing radiat...

background: this research was conducted to evaluate the potential benefits of zinc sulphate in the prevention of radiation induced mucositis in patients who are being treated for head and neck cancers. materials and methods: forty patients with proven cancers of head and neck were randomly divided into 2 equal groups that either received zinc sulphate or placebo (control group). patients who re...

BACKGROUND Oral mucositis is one of the irritating side effects of chemotherapy in patients undergoing bone marrow transplantation. However, up until now, the common methods of oral mucositis therapy have failed to show significant effects. OBJECTIVES The aim of this study was to investigate the effects of local cryotherapy on the intensity of chemotherapy-induced oral mucositis in autologous...

PURPOSE/OBJECTIVES To review novel approaches to assessing and managing patients with cancer who are at risk for oral mucositis. DATA SOURCES Published research and review articles, books, conference presentations, and abstracts. DATA SYNTHESIS Oral mucositis is a major source of clinical morbidity among patients with cancer undergoing treatment, yet definitive management strategies continu...

Oral mucositis makes the patients with cancer of the female reproductive system experience both physical and mental sufferings as well as changing social interaction. The patients have oral pains and problems in chewing and swallowing food (Cella et al., 2003). As a result, the patients’ intake of nutrients and fluid is insufficient for physical needs; causing weariness and fatigue, and also in...

OBJECTIVES/HYPOTHESIS The objective of this study was to perform a meta-analysis of the efficacy of honey in the management of oral mucositis during radiotherapy in patients with head and neck cancer. STUDY DESIGN Meta-analysis using MEDLINE, Scopus, and the Cochrane Library as data sources. METHODS Two authors independently searched the databases for relevant studies from inception to June...

We evaluated the effects of special oral care using a toothbrush with combined irrigation and suctioning functions, along with povidone-iodine to treat oral bacteria and mucositis, in esophageal cancer patients undergoing chemoradiotherapy. In the special care group, oral hygiene was performed 3 days a week after dinner. Bacteria in saliva and plague samples were measured at various sampling po...