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it has been reported that fractures are more common in epileptic patients relative to the general population. seizures by repeated muscular contractions can increase fracture risk throughout the skeleton, but the reported papers about non traumatic vertebral fractures following a single episode of seizure are rare and mostly located in thoracic spine with only one or two vertebral fracture. the...
Specific cell surface labeling is essential for visualizing the internalization processes of G-protein coupled receptors (GPCRs) and for gaining mechanistic insight of GPCR functions. Here we present a rapid, specific, and versatile labeling scheme for GPCRs at living-cell membrane with the use of a split green fluorescent protein (GFP). Demonstrated with two GPCRs, GPR17 and CysLT2R, we show t...
We propose a new active learning method for classification, which handles label noise without relying on multiple oracles (i.e., crowdsourcing). We propose a strategy that selects (for labeling) instances with a high influence on the learned model. An instance x is said to have a high influence on the model h, if training h on x (with label y = h(x)) would result in a model that greatly disagre...
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