CLINICAL CASE A 39-year-old man with Philadelphia chromosome-positive acute lymphoblastic leukemia (LAL Ph+) developed progressive vision loss to no light perception in his right eye. He had optic disk edema and later developed central artery and vein occlusions. Pan-photocoagulation, as well as radiotherapy of the whole brain were performed in several fractions. Unfortunately the patient died ...

The.methods of active contours (“snakes”) and level sets were applied to images of the retina in order to locate the outer boundary of the optic disk. A gradient-vector-flow based acuve contour was used as it performed well over a large range of initial conditions. Images were pre-processed to lessen the influence of blood vessels on boundary detecuon. Both active wntours and level set methods ...

PURPOSE To compare the performance of the retinal nerve fiber layer (RNFL) thickness and optic disk algorithms as determined by optical coherence tomography to detect glaucoma. DESIGN Observational cross-sectional study. METHODS setting: Academic tertiary-care center. study population: One eye from 42 control subjects and 65 patients with open-angle glaucoma with visual acuity of > or =20/4...

Automatic eye screening for conditions like diabetic retinopathy critically hinges on detection and localization of Optic disk (OD). In this paper, we present a novel scale-embedded dictionary-based method that poses the problem of OD localization as that of classification, carried out in sparse representation framework. A dictionary is created with manually marked fixed-sized sub-images that c...

We present a new method for optic disk (OD) detection in a retinal image. It is an hybrid approach which uses properties of both appearance and model-based approaches which are mostly used for OD detection. An extrema pyramidal decomposition is employed and hill type topographical features are extracted at the lowest level of the image pyramid. The detected hill points are characterised as cand...

Quantitative phase spectroscopy is presented as a novel method of measuring the wavelength-dependent refractive index of microscopic volumes. Light from a broadband source is filtered to an ~5 nm bandwidth and rapidly tuned across the visible spectrum in 1 nm increments by an acousto-optic tunable filter (AOTF). Quantitative phase images of semitransparent samples are recovered at each waveleng...

A system of television ophthalmoscopy has been developed using commercially available colour television cameras and a specially designed high-sensitivity monochrome television camera. Funduscopy and fluoroscopy can be performed at low light levels and recorded on standard video tape for clinical evaluation and also as a teaching aid. A computerised television stereo ophthalmoscope image process...

Objective-  To determine the possibility of three-dimensional ultrasonography (3DUS) and measurement of optical nerve sheet by this method. Design- Descriptive study. Animals- 10 mixed normal dogs (5males, 5 females), age 1-1.5 year, and weighting 15±5 kg Procedure- 3D ultrasounds of the eyes were evaluated and the normal optical nerves in 3DUS images were measured using Volouson 730 pro....