an improved, simple, and facile synthesis of 3,4-dihydropyrimidin-2(1h)-ones by employing three-component, one-pot condensation reaction of β-keto ester, aromatic aldehydes, and urea or n-methylurea using lacl3/clch2cooh as an inexpensive and green chemistry catalyst system under solvent-free conditions described. compared with the classicalbiginelli reaction conditions, this method has the adv...

functionalization of multiwalled carbon nanotubes (mwcnts) with nh2 groups under a one pot reaction is studied. during the first step of the reaction, cl and chcl2 groups were attached to the surfaces of mwcnts through an electrophilic addition reaction. in the second step of process, cl atoms were replaced with nh2 and amino groups (ethylene diamine and butyl amine) under a nucleophilic substi...

a series of tri- and tetra- substituted imidazoles were synthesized from benzyl, aldehyde and ammonium acetate in the presence of zeolite as an ecofriendly reusable catalyst under microwave irradiation in the absence of solvent. the yields are high to excellent and the use of microwave irradiation reduces reaction times to few minute.

in the present study, some new bis-imidazole derivatives have been prepared through four-components condensation of 2,6-bis (4-aminophenyl)-4-p-tolylpyridine, benzaldehyde derivatives, benzil and ammonium acetate in presence of acetic acid. the present methodology offers several advantages such as good yields, simple procedure, milder conditions and the possibility of introducing a variety of s...

Nano silica sulfuric acid as a solid acid, was described to be an effective catalyst for one-pot three-component reaction of kojic acid, aryl aldehydes and indoles for the preparation of 2-substituted aryl (indolyl) kojic acid derivatives. The catalyst was prepared by combination of chlorosulfonic acid to nano silica gel. The size of nanoparticles were observed with SEM.All prepared compounds w...

Asavas and arishtas are produced by fermentation in an earthen pot according to textual procedure. The size and shape of the pot and the quantity of the drug. That can be taken in a pot for fermentation is not mentioned in the literature. The present Study was taken up to determine the quantity of drug that can be fermented in an earthen Pot to obtain best results.Dasamularishta was fermented i...

A new, convenient, efficient, and cost-effective one-pot synthesis of 1Hphenanthro[9,10]imidazol-2-yl from phenanthraquinone and aldehydes, using sulfuric acidimmobilized on silica as catalyst is described. The present methodology offers severaladvantages such as excellent yields, simple procedure, shorter reaction times, the use ofinexpensive reagents, easy recovery and eco-friendly. In additi...

1, 4-Diazabicyclo [2.2.2] octane (DABCO) was employed as a catalyst for one-pot synthesis of pyrano[2,3-d] pyrimidinone derivatives and MWNT- pyrimidinones from condensation reactions of aromatic aldehydes, malononitrile and thiobarbituric acid and MWNT-COCl . This method delivers the advantages of a simple method, environment friendly procedure, mild reaction conditions and high returns. The m...

Nanocrystalline alumina powder has been synthesized using solution combustion method. The obtained nanocrystalline alumina powder was used as an efficient catalyst for the synthesis of imidazo[1,2-a]azine derivatives from one-pot three component reaction of benzaldehyde, 2-aminoazine and trimethylsilylcyanide under ultrasonic irradiation and refluxing condition. Reusability of catalyst and shor...

A simple and efficient protocol for the synthesis of N-substituted pyrroles from one-pot condensation reaction of 2, 5-dimethoxytetrahydrofuran with aryl/alkyl, sulfonyl and acyl amines in the presence of ZrOCl2•8H2O in water has been developed. This new method has the advantages of simple experimental and work-up procedure, high to excellent yields, easy availability, economical, eco-frien...