BACKGROUND & AIMS Fatty acid (FA) composition of the spermatozoa may be an important determinant of fertility. The aim was to evaluate polyunsaturated fatty acid (PUFA) composition of the blood plasma and spermatozoa in infertile men with idiopathic oligoasthenoteratozoospermia (OAT). METHODS Eighty-two infertile men with idiopathic OAT and seventy-eight fertile men defined according to semen...

Abstract Study question Is varicocelectomy effective in improving the semen quality of patients with isolated oligozoospermia (IO)? Summary answer Varicocelectomy is a valid option for infertile men clinical varicocele and documented IO considering significant improvement concentration. What known already Varicocele leading correctable cause male factor infertility its surgical treatment has be...

Background: Infertility is a complex medical problem. About 15% of couples are infertile, and male infertility being involved in roughly 50% of the cases. Among these, many cases are associated with a severe impairment of spermatogenesis. During the last stage of spermatogenesis (spermiogenesis), sperm chromatin endures complex modifications in which histones are lost and depositioned with tran...

It is believed that one cause of sperm dysfunction might arise through multiple mitochondrial DNA deletions (Delta mtDNA) resulting in the formation of an incomplete electron transport chain. This study investigates the incidence of multiple Delta mtDNA in human spermatozoa prepared on Percoll gradients. Firstly, we investigated for the presence of two frequently analysed Delta mtDNA, the 4977 ...

Abstract Study question What are the effect and corresponding mechanisms of chromosome chaos sperm caused by mutation MEIKIN gene on preimplantation embryo development? Summary answer Sperm induced mutations directly causes blastocyst formation failure affecting activation embryonic genome lineage differentiation. is known already In mice, Meikin a meiosis-specific kinetochore factor that plays...

I am Borut Peterlin, from Division of Medical Genetics, Department of Obstetrics and Gynaecology, University Medical Center, Ljubljana, Slovenia. We write to you to discuss if the number of CAG repeats in the androgen receptor (AR) gene is associated with male infertility in a group of 190 Slovene infertile men compared to 137 men with proven fertility. Pathophysiology of subfertility involves ...

background: there is growing evidence that damage to spermatozoa by reactive oxygen species (ros) play a key role in male infertility. objective: the aim of the present study was to assess the antioxidant status of seminal plasma by measuring total antioxidant capacity (tac) and activities of catalase and superoxide dismutase (sod) in men with asthenozoospermia, asthenoteratozoospermia and olig...

You have accessJournal of UrologyInfertility: Epidemiology & Evaluation I (MP21)1 Sep 2021MP21-04 SUCCESSFUL SPERM RETRIEVAL FOR MEN WITH Y CHROMOSOME AZFC MICRODELETION I-Shen Huang, Wei-Jen Chen, and William J Huang HuangI-Shen More articles by this author , ChenWei-Jen Chen HuangWilliam View All Author Informationhttps://doi.org/10.1097/JU.0000000000002006.04AboutPDF ToolsAdd to favoritesDow...

Background: Worldwide, infertility affects about 15% of reproductive-age couples. In many cases, can't be treated, however new treatment options with promising value have been involved in recent clinical trials. The aim this trial was to evaluate the impacts adding coenzyme Q10 (CoQ10) to letrozole on results spermiogram and ...