A statistical programme using Box-Behnken design, which applies a response optimization algorithm, was used to calculate and optimize simultaneously the lactic acid extraction by emulsion liquid membrane (ELM) in a mixed flow reactor. A 3-level Box-Behnken design with seven variables i.e. lactic acid concentration, internal reagent concentration, Alamine 336 fraction in oleyl alcohol, stirring ...

In this study, we examined three kinds of stabilizing additives to prepare stable MRF with good fluidity. We selected additives; a styrene isoprene block copolymer, hydrophobic fumed silica, and an organogelator (CMOL SB03; PMDA-2C 8 /oleyl). measured the rheological properties both for dissolutions in base oil MRFs prepared by using rheometer; MCR302 (Anton Paar Corp.). From experimental resul...

Abstract This work probes the potential of fluorous fatty acids as stabilizing ligands in synthesis mixed halide perovskite quantum dots (MHP QDs). Traditionally, MHP QDs are synthesized presence oleic acid (OA) and oleyl amine (OAm). Here have been used along with OA OAm to yield higher stability. Increased fractions molecules reaction mixture require process be carried out at a temperature du...

Background: Alcohol is a potent teratogen and alcohol use in pregnancy and the periconception period can cause many complications in mother, fetus and neonate.  Discussion: Alcohol in the mother's blood passes through the placenta to the baby through the umbilical cord. Drinking alcohol during pregnancy can cause miscarriage, stillbirth, and a range of lifelong disorders. Alcohol-related birth ...

the international data have indicated a growing trend of alcohol use worldwide during recent years. although alcohol use is against cultural norms and religious law in iran, anecdotal reports from substance abuse treatment providers show that there is demand for alcohol treatment in the country. a recent national report also documented alcohol use disorders in iran. development and implementati...

Anandamide and other polyunsaturated N-acylethanolamines (NAEs) exert biological activity by binding to cannabinoid receptors. These receptors are linked to G(i/o) proteins and their activation leads to extracellular-signal-regulated protein kinase (ERK) and c-Jun N-terminal kinase (JNK) mitogen-activated protein kinase (MAP kinase) activation, inhibition of cAMP-dependent signalling and comple...

Topical drug dosage forms such as ointments and creams can be easily removed through wetting, movement and contact. The new bioadhesive formulations with enhanced local anesthetic effects are needed for topical administration. The adhesive capacity of hydroxypropyl methylcellulose (HPMC) was determined by measuring the maximum detachment force and the adhesion work with an auto peeling tester. ...

Many hydrophobic drugs encounter severe bioavailability issues owing to their low aqueous solubility and limited cellular uptake. We have designed a series of amphiphilic polyaspartamide polyelectrolytes (PEs) that solubilize such hydrophobic drugs in aqueous medium and enhance their cellular uptake. These PEs were synthesized through controlled (∼20 mol %) derivatization of polysuccinimide (PS...