نتایج جستجو برای: od ماده کانژوگه

تعداد نتایج: 44772  

2013
Andreas Karabis Leandro Lindner Michelle Mocarski Eline Huisman Andrew Greening

BACKGROUND Aclidinium bromide is a new long-acting muscarinic antagonist (LAMA) indicated for maintenance bronchodilator treatment of chronic obstructive pulmonary disease (COPD). The efficacy of aclidinium was compared with tiotropium and glycopyrronium, using a network meta-analysis (NMA) of randomized controlled trials (RCTs) in moderate-to-severe COPD patients. METHODS A systematic review...

2009
W Kruis G Kiudelis I Rácz I A Gorelov J Pokrotnieks M Horynski M Batovsky J Kykal S Boehm R Greinwald R Mueller

OBJECTIVES To determine the therapeutic equivalence and safety of once daily (OD) versus three times daily (TID) dosing of a total daily dose of 3 g Salofalk (mesalazine) granules in patients with active ulcerative colitis. DESIGN A randomised, double-blind, double-dummy, parallel group, multicentre, international, phase III non-inferiority study. SETTING 54 centres in 13 countries. PATIE...

Journal: :Chest 1986
B T Mangura T Maniatis M S Abdel Rahman R Bartholf M H Lavietes

To evaluate the bioavailability of a new theophylline preparation suitable for once-a-day (od) oral administration, we performed a nonrandomized crossover study in which the absorption of the OD and a standard twice-a-day (bid) preparation were compared. Eight stable asthmatic patients, after having achieved steady-state, received an average of 975 mg of OD preparation at 8 PM. The protocol was...

2007
S. Balasubramaniam Anantha Vidya Sagar V. Chandrasekaran

Locating the Optic Disc (OD) is of critical importance in a retinal analysis system. This paper presents a fast algorithm for the automatic localization of OD in digital fundus retinal images. OD localization follows the Blood Vessel Detection (BVD). A morphology based approach is proposed for BVD. OD is localized by exploiting the property that it is a bright region and the density of blood ve...

2012
Neelam Sinha R. Venkatesh Babu

Automatic eye screening for conditions like diabetic retinopathy critically hinges on detection and localization of Optic disk (OD). In this paper, we present a novel scale-embedded dictionary-based method that poses the problem of OD localization as that of classification, carried out in sparse representation framework. A dictionary is created with manually marked fixed-sized sub-images that c...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2014
Franziska Greifzu Justyna Pielecka-Fortuna Evgenia Kalogeraki Katja Krempler Plinio D Favaro Oliver M Schlüter Siegrid Löwel

Ocular dominance (OD) plasticity in mouse primary visual cortex (V1) declines during postnatal development and is absent beyond postnatal day 110 if mice are raised in standard cages (SCs). An enriched environment (EE) promotes OD plasticity in adult rats. Here, we explored cellular mechanisms of EE in mouse V1 and the therapeutic potential of EE to prevent impairments of plasticity after a cor...

2014
Hao Zhu Qing-Hua Liang Xin-Gui Xiong Jiang Chen Dan Wu Yang Wang Bo Yang Yang Zhang Yong Zhang Xi Huang

Objectives. This study aimed to identify the active compounds in Oldenlandia diffusa (OD) decoction and the compounds absorbed into plasma, and to determine whether the absorbed compounds derived from OD exerted any anti-inflammatory effects in rats with collagen induced arthritis (CIA). Methods. The UPLC-PDA (Ultra Performance Liquid Chromatography Photo-Diode Array) method was applied to iden...

Journal: :Plant physiology 2010
Jin-Ho Kang Guanghui Liu Feng Shi A Daniel Jones Randolph M Beaudry Gregg A Howe

Glandular secreting trichomes of cultivated tomato (Solanum lycopersicum) produce a wide array of volatile and nonvolatile specialized metabolites. Many of these compounds contribute to the characteristic aroma of tomato foliage and constitute a key part of the language by which plants communicate with other organisms in natural environments. Here, we describe a novel recessive mutation called ...

Journal: :Canadian journal of public health = Revue canadienne de sante publique 2006
Benedikt Fischer Svetlana Popova Jürgen Rehm Andrew Ivsins

OBJECTIVE To compare rates of fatal drug-related overdose death (OD) cases--a major harm outcome of illicit substance use--in the two provinces of British Columbia (BC) and Ontario, and the two largest municipalities in those provincial jurisdictions, namely the cities of Vancouver and Toronto, between 1992 and 2004. METHODS Provincial coroners' data of drug-related OD cases for the provincia...

Journal: :Journal of medical imaging 2018
Fantin Girard Conrad Kavalec Farida Cheriet

Optic disc (OD) appearance in fundus images is one of the clinical indicators considered in the assessment of retinal diseases such as glaucoma. The cup-to-disc ratio (CDR) is the most common clinical measurement used to characterize glaucoma. However, the CDR only evaluates the relative sizes of the cup and the OD via their diameters. We propose to construct an atlas-based shape descriptor (AS...

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