Topical all-trans retinoic acid (RA) produces a number of epidermal changes which are indistinguishable from those observed following treatment with a local irritant, namely sodium lauryl sulphate (SLS). This observation has led to criticism that the efficacy of RA in disorders such as photoageing, is merely a result of irritancy. In stratified epithelia, the cellular differentiation process is...

Introduction: Patients with bilateral weakness (BW) have many difficulties in gaze stability that interfere with their normal function. The aim of this study was to evaluate ocular motor functions in patients with BW to better understand the problem of gaze instability in these patients.   Materials and Methods: Patients were referred from the Otolaryngology Department for Vestibular Assessmen...

forty patients with cataracts, as well as 40 patients with proven ocular toxoplasmosis were enrolled in this prospective clinical study. serum igg and aqueous igg in both groups were measured by enzyme-linked immunosorbent assay (elisa) and the corresponding ratios were calculated. serum igg/aqueous humor igg ratio was less than 100 in the patient group and more than 100 in the control group. o...

purpose: there are a few researches regarding the effects of islamic fasting on visual system. the aim of this study was to investigate the effects of ramadan fasting on the amplitude of accommodation (aa), near point of convergence (npc), positive and negative fusional vergences (pfv and nfv, respectively) in visually healthy fasters. methods: aa, npc, pfv and nfv at far (6m) and near (40cm) w...

cutaneous leishmaniasis (cl) is the most common parasitic disease transmitted by vectors in iran. cl is endemic in many urban and rural parts of iran and usually caused by two species of leishmania as l . major and l . tropica transmitted to humans from parasite reservoirs by the bite of female sandflies. we report a case of ocular leishmaniasis with eyelid involvement presentation. the patient...

purpose: to compare the efficacy of intravitreal clindamycin and dexamethasone with classic treatment for ocular toxoplasmosis. methods: in this prospective, randomized single-masked clinical trial a total of 68 patients with active ocular toxoplasmosis were assigned randomly to 2 treatment groups: 34 in the intravitreal clindamycin plus dexamethasone (ivcd) group and 34 in the classic treatmen...

purpose: to compare the effects of short-tem and long-term systemic corticosteroids in the treatment of confirmed ocular toxoplasmosis. methods: this randomized comparative clinical trial was performed on 69 patients with confirmed active ocular toxoplasmosis with typical clinical manifestations. the subjects were randomly assigned to receive either 10 days (group a, 33 cases) or 4-6 weeks (gro...

Background: Thyroid-associated eye disease (TED), previously known as Graves’ ophthalmopathy is a cosmetically and functionally debilitating disease that is seen worldwide. The aim of this study was to evaluate the prevalence and clinical severity of ocular manifestations of Graves’ disease according to sex, age and duration in northern Iran. Methods: Between April 2011 and March 2...

Topical applications of the drugs have an advantage delivering drug directly to site action and acting for a longer period time. Skin is one most widespread readily accessible organs on human body topical administration main route delivery system. The aim this project was formulate natural safe herbal skin toner which has calming, soothing, astringent, effect face reduce facial irritancy enhanc...