Background and objective:Many biochemical features of sulfur mustard (SM) intoxication remained unknown. So far, the direct association between biochemical parameter changes and ocular problems in patients exposed to SM is not evaluated.The current study aimed at evaluating the associations between the ocular findings in patients with SM intoxication and the changes of...

AIM to investigate correlations between changes in ocular hemodynamics revealed by color Doppler flow mapping (CDFM) and pulsed-wave (PW) Doppler imaging, one the one hand, and electrical activity of the retina, on the other, in patients with early, moderate, and severe retinitis pigmentosa (RP). MATERIAL AND METHODS A total of 20 patients (40 eyes) aged from 16 to 40 years (28.4 ± 8.2 years ...

Impairments of autoregulation and neurovascular coupling in the optic nerve head play a critical role in ocular pathologies, especially glaucomatous optic neuropathy. We critically review the literature in the field, integrating results obtained in clinical, experimental, and theoretical studies. We address the mechanisms of autoregulation and neurovascular coupling in the optic nerve head, the...

Cranial Arterial Circulation and Ocular Pulsations in the Dog • The form of the ocular pulse in anesthetized dogs resembled an arterial pressure tracing. Obstructing the carotid artery reduced the amplitude of the pulse in the ipsilateral eye, but if collateral circulation through the basilar artery remained intact, the pulse soon returned to normal. Division of the basilar artery by itself tem...

Naturally occurring collatera l pathways con necting the external carotid artery branches and the intracran ial cerebral circulation are well recognized and have been demonstrated anatomically, angiographically, and physiologically by vari­ ous flow detection devices. Under normal c ircumstances, all internal carotid artery blood flow is direc ted intracranially, and flow through the co ll ater...

BACKGROUND AND OBJECTIVE Vitrectomy markedly alters the intraocular milieu, which can then affect the physiology of the retina and choroid. This study investigates whether vitrectomy also alters ocular blood flow as determined by laser speckle flowgraphy (LSFG). PATIENTS AND METHODS Twenty eyes of 20 patients that underwent vitrectomy for idiopathic macular hole or epiretinal membrane were st...

Effects of increments in intraocular pressure on the blood flow in the retina and. the distal part oj the optic nerve were investigated in monkeys with the use of untabeled microspheres. Moderate elevations in intraocular pressure which reduced the perfusion pressure (mean arterial blood, pressure — intraocular pressure) to levels above 40 cm H2O had only small effects in the retina and. the pr...

There are two long-standing theories about the pathogenesis of glaucoma - barotrauma and the effect of vascular hypoxia. Currently, it is still unknown whether diminished blood flow is the cause or result of glaucomatous atrophy of ganglion cells and the optic nerve. Though many other imaging techniques used to directly assess ocular blood flow have been well studied, they are limited by their ...

Background The involvement of nitric oxide (NO) in choroidal blood flow regulation during experimental increase of ocular perfusion pressure (OPP) has been shown in previous studies. It is also known that during isometric exercise, the inhibition of NO synthase (NOS) leads to a rightward shift of pressure-flow curves. In this study the influence of inhibited NOS on optic nerve head (ONH) blood ...

Background: Rheumatoid Arthritis patients are evaluated during treatment for various inflammatory factors such as C-reactive protein, Erythrocyte Sedimentation Rate, and Disease Activity Score, and other immune system-related factors. In the follow-up of patients with rheumatoid arthritis, hematologic factors associated with the immune system especially Platelet to Lymphocyte Ratio and Neutroph...