ABSTRAK Latar Belakang: Kanker kolorektal menduduki posisi ketiga kanker tersering dan keempat yang paling sering menyebabkan kematian diseluruh dunia yaitu sekitar 700.000 setiap tahunnya. Penyakit ini merupakan salah satu keganasan saluran pencernaan terbentuk melalui berbagai macam faktor seperti genetik lingkungan. Penatalaksanaan hingga saat dilakukan dengan terapi operasi adjuvan memiliki...

Present transplant study was carried out across Lucknow, the capital of Utter Pardesh using two medicinally important plants viz., ?Catharanthus roseus L.? and ?Ocimum sanctum L.? to assess whether certain ecophysiological responses (change in total flavonoids and total phenolics) in these two plants may serve as the biomarkers of auto exhaust pollution. Samples were taken from five different s...

Ocimum sanctum L. var. cubensis (OS) is a valuable medicinal plant. Some varieties have been reported and some of them remain almost unstudied. The aim of this study is therefore to evaluate the chemical composition and the in vitro/in vivo toxicity of the leaves essential oil from O. sanctum, up growing wild in the Eastern region of Cuba. The essential oil was extracted by in a Clevenger type ...

The mast cell has long been associated with asthma, since it releases a variety of preformed and newly synthesized mediators that account for several features of asthma. Among the mediators, histamine is a wellcharacterized and the most potent vasoactive mediator in acute bronchoconstriction. In the present study, albino rats were sensitised by horse serum along with triple antigen containing B...

The present study was aimed to study the acute and subacute toxicity studies with orally administered 50% ethanolic leaves extract of Ocimum sanctum Linn (OSE). In acute toxicity tests, four groups of mice (n = 6/group/sex) were orally treated with doses of 200, 600, and 2000 mg/kg, and general behavior, adverse effects, and mortality were recorded for up to 14 days. In subacute toxicity study,...

Ethanol extracts of Ocimum sanctum Linn. and Tinospora cordifolia (Willd.) Miers ex Hook. f. & Thoms. were included for the present in vitro study. Pepsin was used as a substitute for HIV-protease to evaluate inhibitory activity of these extracts, as pepsin has close resemblance with HIV-protease in proteolytic activity. Extracts of O. sanctum and T. cordifolia showed potent inhibitory activity...

The present study was aimed to establish the antagonistic effects of Ocimum sanctum L. essential oil (OSEO) on growth and zearalenone (ZEA) production of Fusarium graminearum. GC-MS chemical profiling of OSEO revealed the existence of 43 compounds and the major compound was found to be eugenol (34.7%). DPPH free radical scavenging activity (IC50) of OSEO was determined to be 8.5 μg/mL. Minimum ...