Acrylates andmethacrylates are the salts, esters and conjugate bases of acrylic acid and methacrylic acid, respectively. They are well known to cause allergic contact dermatitis (ACD) (1). Occupational contact dermatitis (OCD) resulting from the use of (meth)acrylates has been widely reported in beauticians and ‘nail artists’. According to The Health and Occupation Research database, the freque...

We discuss allergic contact dermatitis to the iPad to highlight a potential source of nickel exposure in children.

Cosmetics are an important cause of allergic contact dermatitis (ACD). Fragrances and preservatives are the two most clinically relevant allergens found in cosmetic products. Patch testing remains the gold standard for identification of causative allergens. Common cosmetic allergens are reviewed. Practical methods of allergen avoidance are also discussed.

An 8-year-old girl attended a Halloween party (Fig. 1) where her facewas decoratedwith a colourmake-up pencil. On removing the make-up, she developed erythematous, scaly, itchy patches on the cheeks and perioral area. Hermother applied argan oil on the lesions for some days, which causedaworseningof the rash. Thegirlwas treated in our department with methylprednisolone aceponate cream. Use of t...

To evaluate the role of electrophilicity in the induction of allergic contact dermatitis (ACD) in humans, we compared the structure-activity relationship (SAR) model of ACD with those of electrophilic and nonelectrophilic subsets of chemicals in the ACD database. For these analyses, electrophilicity was defined as the potential of a chemical to induce mutations in Salmonella. It was found that ...

Although acrylic monomers are strong skin sensitizers (1), their corresponding fully cured polymers are considered to be inert. Until recent years, allergic contact dermatitis caused by acrylates, the term comprising, in the following, also methacrylates, was primarily an occupational disease among dentists, printers, and fiberglass workers (2). In our practice, there has been a steady increase...

The aim of this review is drawing the attention to the contact dermatitis, an inflammatory skin condition due to pro-inflammatory and toxic factors able to activate the skin innate immunity (irritant contact dermatitis) or caused by a T-cell- mediated hypersensitivity reaction (allergic contact dermatitis). The immune system involvement and a variety of clinical pictures are described in order ...