In order to describe variation in AP and ICP during OSA, six patients with severe OSA were examined, with determination of ICP, AP, CVP, respiration, tcPO2, tcPCO2, and nocturnal sleep polygraphy. During apnea, elevations of AP and ICP were observed, related to the apneic episodes. The elevations in pressure were only observed in relation to apneic episodes. While awake, none of the patients sh...

Ten patients with autonomic nervous system dysfunction (familial dysautonomia, juvenile diabetes, or Shy-Drager syndrome) were studied to assess the impact of their impairment on breathing during sleep. Several types of breathing dysfunction during sleep were identified independent of the patients' primary complaints. Obstructive sleep apnea syndrome was the most common; central sleep apnea and...

Obstructive sleep apnea syndrome is a common disorder with significant health consequences and is on the rise in consonance with the obesity pandemic. In view of the association between sleep-disordered breathing and pulmonary hypertension as depicted by multiple studies, current clinical practice guidelines categorize obstructive sleep apnea as a risk factor for pulmonary hypertension and reco...

INTRODUCTION: Psoriasis is a chronic, immune-mediated inflammatory disease characterized by sharply circumscribed erythematous plaques on the trunk and limbs. Reports are suggesting low sleep quality increased risk of Obstructive Sleep Apnea Syndrome (OSAS) in psoriasis patients. 
 METHODS: The present study aimed to investigate array OSAS based STOP-Bang questionnaire. was cross-sectional...

The Vaccine and Related Biologic Products Advisory Committee meets at least once a year to decide the composition of the influenza vaccine in the U.S. Past evidence suggests that the Committee could use a more systematic approach to incorporate observed information and to quantify the risks associated with different options. There are two key tradeoffs involved in this decision. One, if the Com...

Standard models of choice assume that the weight given to information from different sources depends exclusively on its diagnosticity. In this paper we study whether the same piece of information is weighted more heavily simply because it was directly experienced rather than merely observed. We investigate this possibility by conducting repeated game experiments in which groups of players are r...

On the basis of the half-Cauchy distribution, we propose the called beta-half-Cauchy distribution for modeling lifetime data. Various explicit expressions for its moments, generating and quantile functions, mean deviations, and density function of the order statistics and their moments are provided. The parameters of the new model are estimated by maximum likelihood, and the observed informatio...

OBJECTIVES/HYPOTHESIS Sleep apnea is associated with hypertension and diabetes, putting these patients at high risk for developing cardiovascular disease. The goal of this study was to identify the individual cardiovascular risk profile and to detect premature and undiagnosed disease in patients with various degrees of sleep apnea. STUDY DESIGN Cross-sectional. METHODS Over a 6-month period...

STUDY OBJECTIVES The objective was to investigate the prevalence of heart attack, angina pectoris, stroke, hypertension, diabetes mellitus, chronic obstructive pulmonary disease, asthma and obesity in relation to the presence and severity of obstructive sleep apnea. METHODS The sample consisted of 1887 patients, with mean age of 48.6 years (range 16-83 years), referred to a university hospita...