The hydrolysis of the nucleoside triphosphates, such as ATP or GTP, plays a central role in a variety of biochemical processes; but, in most cases, the specific mechanism of energy transduction is unclear. DNA strand exchange promoted by the Escherichia coli recA protein is normally associated with ATP hydrolysis. However, we advanced the idea that the observed ATP hydrolysis is not obligatoril...

The aim of this study was to identify the relative impact of adrenergic and cholinergic activity on atrial fibrillation (AF) inducibility and blood pressure (BP) in a model for obstructive sleep apnea. Obstructive sleep apnea is associated with sympathovagal disbalance, AF, and postapneic BP rises. Renal denervation (RDN) reduces renal efferent and possibly also afferent sympathetic activity an...

The scarcity and contamination of water, aggravated by the effects Climate Change, endanger food supply, cause health problems to humans, are a critical concern. New research has been carried out improve quality water used in agricultural sector. One them is technology non-thermal plasma (NTP) generated corona discharges using air as working gas. In this study, NTP applied directly causing acti...

It is indeed a pleasure and a privilege to be asked to give this lecture in memory of a fine medical scientist, whose career was cut so sadly short by violence. In looking at the program today I cannot help but think of another scientist, to whom this field owes so much, whose life was also cut short unexpectedly. Alick Isaacs, the discoverer of interferon, was a brilliant medical scientist and...

-Peripheral-blood basophils were counted, in thick smears, in samples from patients with primary bronchial carcinoma, from patients in the same wards and from normal individuals. The median counts for patients with other chest conditions (15-5/4d) and bronchial-carcinoma patients free of tumour months to years after resection (16/1l) did not differ from those for normal individuals (19/1,u), bu...

The National Toxicology Program has broad responsibilities for expanding the toxicological database on the cor impact of chemical interactions with biological systems, providing data that strengthen the scientific foundation P .# for regulatory decisions, developing and validating alternative test systems, and communicating strategies and C i g c findings to the scientific community, regulatory...

Recently sulfolane has been detected in well water within the town of North Pole, Alaska. A plume was identified in groundwater, originating from a petroleum refinery, and the highest concentration measured in wells outside the refinery was 269 ppb as of January 2011. Due to the contamination, residents were being provided bottled water for use and additional wells were created outside the plum...