Clinicians have used serum creatinine in diagnostic testing for acute kidney injury for decades, despite its imperfect sensitivity and specificity. Novel tubular injury biomarkers may revolutionize the diagnosis of acute kidney injury; however, even if a novel tubular injury biomarker is 100% sensitive and 100% specific, it may appear inaccurate when using serum creatinine as the gold standard....

Immune destruction of the graft renal tubules is an important barrier to the long-term function of clinical renal allografts, but the underlying mechanisms remain obscure. CD103-an integrin conferring specificity for the epithelial cell-restricted ligand, E-cadherin-defines a subset of CD8 effectors that infiltrate the graft tubular epithelium during clinical rejection episodes, predicting a ca...

a case of renal tubular acidosis (rta) who had gradual onset of paralysis of lower extremities and persisted for a long time is presented. his primary workups were mistaken for muscular dystrophy. eventually, an abdominal ultrasonography revealed small stones in both of the kidneys and his workup for the stones were in favor of distal renal tubular acidosis and advanced rickets with hypokalemia...

Epithelial inclusions were detected in myocardium of a 2-month-old male Holstein calf. Microscopically,nonpurulent myocarditis along with focal tubular and acinar structures covered with cuboidal epithelial cellswas seen in the myocardium. Most tubular and acinar structures stained with Masson’s trichrome were foundto be surrounded with a dense collagen. Tubular and acinar structures had PAS po...

Cylindrical Kresling origami structures are often used in engineering fields due to their axial stretchability, tunable stiffness, and bistability, while radial closability is rarely mentioned date. This feature enables a valvelike function, which inspired this study develop new origami-based valve. With the unique one-piece structure of origami, valve requires fewer parts, can improve its tigh...