Hydrophilic/hydrophobic patterning is a powerful strategy to control folding in non-natural polymers/oligomers. In this contribution, we present a novel strategy for the preparation of alternating hydrophilic/hydrophobic patterned non-natural peptide foldamers. This strategy relies on the post-modification of a reactive peptide precursor that can be prepared via standard solid phase peptide syn...

We have investigated the sensing performance of protein-based microcantilever biosensors prepared from multiple surface conjugation chemistries. The 11-mercaptoundecanoic acid monolayers were prepared according to both traditional and modified processes. In three protein-based biosensors, the modified process improved microcantilever sensing performance by increasing the bending amplitude, a cr...

Metrics plays an important role in the software modularization. Several metrics have been discussed so far. This paper describes a metrics based on control structures which is a minor modification of McCabe’s approach. Proposed novel approach is a control structure based complexity (CSBC) which is used to compute the complexity by counting the control structures directly from the source code ra...

The authors examined the effectiveness of a novel behavior modification method for dysfunctional and impulsive habits, based on nonremovable reminders (NrRs). NrRs were implemented by having participants wear nonremovable wristbands designated to constantly remind them of their resolution to quit the targeted habit (nail-biting). Participants were 80 nail-biters who resolved to quit. The NrR ap...

This article describes a novel approach to humanrobot interaction, in which a user modifies a robot’s environment to constrain its actions, rather than programming its controller. An HRI simulation of a maze navigation task is presented. An empirical evaluation shows that for this task, users prefer an environment modification strategy rather than a programming strategy as the difficulty of the...

In an important and much cited paper Vladimir Lifschitz and Hudson Turner have shown how, under certain conditions, logic programs under answer set semantics can be split into two disjoint parts, a “bottom” part and a “top” part. The bottom part can be evaluated independently of the top part. Results of the evaluation, i.e., answer sets of the bottom part, are then used to simplify the top part...

The speech recognition accuracy has been observed to decrease for nonnative speakers, especially those who are just beginning to learn foreign language or who have heavy accents. This paper presents a novel bilingual model modification approach to improve nonnative speech recognition, considering these great variations of accented pronunciations. Each state of the baseline nonnative acoustic mo...

This paper presents a novel tangible interaction technique leveraging Near Field Communication (NFC) enabled Magnetic Cards to empower elderly end-users in programming their pervasive computing environment. Following a user-centric design approach through cultural probes, we have explored the design space of possible programming opportunities for elderly users. Accordingly we have identified in...

This course sets out with an examination of the role of events in accounting for inferential properties of modification. It presents a model of the logic of modification following the neo-Davidsonian mode of composition but reworking the Davidsonian framework. The approach is shown to accord with more intuitively appealing notions of event individuation and to afford a uniform treatment of indi...