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Rhp14 of Schizosaccharomyces pombe is homologous to human XPA and Saccharomyces cerevisiae Rad14, which act in nucleotide excision repair of DNA damages induced by ultraviolet light and chemical agents. Cells with disrupted rhp14 were highly sensitive to ultraviolet light, and epistasis analysis with swi10 (nucleotide excision repair) and rad2 (Uve1-dependent ultraviolet light damage repair pat...
Leptospirosis is a worldwide zoonosis caused by pathogenic Leptospira. The whole-genome sequence of L. interrogans serovar Copenhageni together with bioinformatics tools represent a great opportunity to search for novel antigen candidates that could be used as subunit vaccine against leptospirosis. We focused on six genes encoding for conserved hypothetical proteins predicted to be exported to ...
Intracellular delivery of functional macromolecules using peptide transduction domains (PTDs) is an exciting technology with both experimental and therapeutic applications. Recent data indicate that PTD-mediated transduction occurs via fluid-phase macropinocytosis involving an intracellular pH drop to approximately 5. Nitrilotriacetic acid (NTA)-coordinated metals avidly bind hexahistidine-tagg...
IN AN ARTICLE published in this journal in 1997, drawing on data from China’s 1982 One-per-Thousand-Population Fertility Survey, I argued that the highfertility regime existing before China’s nationwide family planning campaign was introduced could have involved deliberate fertility control. James Lee, Feng Wang, and Cameron Campbell reached a similar conclusion (Wang, Lee, and Campbell 1995; L...
the effect of learning strategies on the speaking ability of iranian students in the context of language institutes abstract language learning strategies are of the most important factors that help language learners to learn a foreign language and how they can deal with the four language skills specifically speaking skill effectively. acknowledging the great impact of learning strategies...
august wilson is undoubtedly one of the rare black playwrights whose works have attracted streams of attention and worldwide audience. the present study aims at analyzing fences and piano lesson which are two of the most successful plays in his pittsburgh cycle from the perspective of michel foucault’s theories and ideas. studying these two plays from foucault’s perspective opens new windows in...
Professor Dr. Yan-Ling Liang, our family-like friend, respected colleague, and renowned mentor, passed away suddenly peacefully in Wuhan, Hubei Province, China, on 8 December 2021, at the age of 88, survived by his wife, two sons, grandchildren.
according to cheng (1999), in recent esl/efl literature, asian (especially east asian) learners of english as a foreign/second language have been arguably reported as reticent and passive learners. the most common allegations are that these students are reluctant to participate in classroom discourse; they are unwilling to give responses; they do not ask questions; and they are passive and over...
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