We infused dobutamine (20 microgram/kg per min) intravenously, once before and once after coronary artery occlusion, in 10 chronically instrumented dogs. Both infusions increased cardiac output and left ventricular dP/dt and dP/dt/P, but divergent effects on heart rate and aortic blood pressure were observed. Dobutamine decreased heart rate and increased mean aortic blood pressure before corona...

Few studies have examined metabolic consequences of coronary occlusion and reperfusion using phosphorus31 nuclear magnetic resonance (31P-NMR) in an intact animal model. Accordingly, we developed a model to study serial changes in myocardial metabolism in the intact open-chest rabbit. Ten animals underwent 20 +/- 2 minutes of regional coronary occlusion and 60 +/- 10 minutes of reperfusion foll...

For a large Adaptive Optics (AO) system such as a large Segmented Mirror Telescope (SMT), it is often difficult, although not impossible, to directly apply common Multi-Input Multi-Output (MIMO) controller design methods due to the computational burden imposed by the large dimension of the system model. In this paper, a practical controller design method is proposed which significantly reduces ...

In a previous study occlusion of a middle cerebral artery (MCA) followed by 48 h of hypothermia (29 degrees) was lethal in 5 of 5 monkeys as compared to only 3 of 9 normothermic animals. The present study extended these observations in monkeys and cats with or without MCA occlusion. In monkeys MCA occlusion plus 48 h of hypothermia was consistently lethal. Without MCA occlusion of 2 of 3 monkey...

chronic total occlusion (cto) intervention is still a challenging problem. the aim of this study is to determine factors that affect pci results.the study was conducted on 72 patients in two centers. cto angioplasty was done by the antegrade approach from the femoral and/or radial approach. the role of age, gender, anatomical variations such as calcification, length of the lesion, proximal bend...

background: in vitro fertilization and embryo transfer (ivf-et) is the best option for patients with hydrosalpinx. however, if hydrosalpinges is not pre-treated, the therapeutic outcomes of ivf-et would be compromised. objective: this study aims to investigate the safety and effects of operative hysteroscopy in the treatment of patients with hydrosalpinx prior to ivf-et, who were not indicated ...

Seven dogs were instrumented with a left ventricular micromanometer, pairs of ultrasonic crystals to measure wall thickness in normal and ischemic regions, as well as both short and long axes of the left ventricle; and cuff occluders were placed around the left circumflex coronary artery and the inferior vena cava. Left ventricular volume, mass, circumferential wall stress, midwall strain, and ...

OBJECTIVE Pulmonary artery occlusion pressure and central venous pressure have been considered to be reliable measures of left and right ventricular preload in patients requiring invasive hemodynamic monitoring. Studies in recent years have questioned the correlation between these estimates of ventricular filling pressures and ventricular end-diastolic volumes/cardiac performance variables in s...

The relation of angiographically recognized coronary occlusion to regional myocardial blood flow has not been studied adequately in spite of its clinical significance. This is particularly important, as revascularization procedures, based on angiographic studies, are being performed with increasing frequency. To compare the severity of reduction in flow to the severity of coronary occlusion, re...

Unilateral naris occlusion, a standard method for causing odor deprivation, also alters airflow on both sides of the nasal cavity. We reasoned that manipulating airflow by occlusion could affect nasal turbinate development given the ubiquitous role of environmental stimuli in ontogenesis. To test this hypothesis, newborn mice received unilateral occlusion or sham surgery and were allowed to rea...