Cadmium (Cd) is an environmental and industrial pollutant that affects the male reproductive system. Exposure to cadmium metal is known to induce the formation of reactive oxygen species (ROS) like superoxide radical, hydroxyl ion and hydrogen peroxide. Vitamin E is a lipid phase antioxidant & Vitamin C acts as a potent water soluble antioxidant by scavenging reactive oxygen species. The purpos...

The aims of this study were to investigate the adverse effects of sodium arsenite on the reproductive system of male rats as well as to examine whether vitamin E is able to ameliorate these effects. Adult rats were divided into four groups: 1/ control, 2/ sodium arsenite (8 mg/kg/day), 3/ vitamin E (100 mg/kg/day), and 4/ sodium arsenite +vitamin E group. Treatments were administered orally by ...

Over the past decades several studies have investigated the importance of an adequate vitamin E status to sustain both animal health and production in dairy cows. Cow milk is considered as a remarkable source of bioactive components promoting human health, which has renewed interest in the effects of vitamin E supplementation on its nutritional value, sensory quality and shelf life. Thus, defin...

The hypothesis that vitamin E acts mainly as a physiological antioxidant suggests that, in its absence, loss of many types of oxidizable substances may occur. Considerable importance has been attached, in this connexion, to the polyunsaturated fatty acids (PUFA), because of their chemical structure and because of their biochemical role in structural elements of the cell. Pritchard & Singh (1960...

Objective: Age brings about changes to the oxidant and antioxidant balance of male testis that give rise loss fertility. The Ferula elaeochytris root extract (FE), contents anti-inflammatory component, have been used treat infertility by local people for centuries. main objectives this study were determine whether FE was effective on sperm quality, spermatogenesis, apoptosis oxidative stress in...

Objective Vitamin E is a major lipid-soluble antioxidant. It has been demonstrated that vitamin E supplementation has a beneficial effect against coronary heart disease (CHD). This study to investigate the effects of coronary risk factors on serum vitamin E status in patients with dyslipidaemia. Materials and Methods This tertiary care hospital; case - control study was comprised 237 dyslipidae...

Vitamin E serves an important role in protecting the cellular membrane constituents from peroxidative damage. Biochemical and functional studies were performed on polymorphonuclear leukocytes (PMN) from vitamin-E deficient and control rats to investigate the consequences of uncontrolled peroxidation of the rat PMN membrane. Rats fed a vitamin-E-deficient diet for 2 mo had serum tocopherol level...

Natural dietary ingredients are known for their antioxidant activity. Of such, curcumin, the active principle of turmeric, at 0.01% in the diet proved as pro-oxidative in galactose-induced cataract in vivo. The purpose of this study was to investigate the effect of vitamin E (VE), a well-known antioxidant, in combination with curcumin on the onset and maturation of galactose induced cataract. P...

In an experimental model of atherogenesis induced by hyperfibrinogenemia (HF), the pharmacological response of vitamin E was studied in order to assess its antioxidant effect on the mitochondrial morphofunctional alterations in aortic smooth muscle cells. Three groups of male rats were used: (Ctr) control, (AI) atherogenesis induced for 120 days, and (AIE) atherogenesis induced for 120 days and...