Leaves of Premna integrifolia belong to Verbanacea is an important rasayana drug in ayurvedic medicine and are considered to be useful in the treatment of variety of ailments. The present study was aimed to assess the for its antioxidant activities. The flavonoid rich fraction, showed antioxidant activity was evaluated using the superoxide scavenging, anti lipid peroxidation, hydroxyl radical s...

One rare flavonoid-diterpene heterodimer, denticulatain C (1), one modified geranyl-type side chain substituted flavonoid, denticulatain D (2) and one geranylated flavonoid, denticulatain E (3), as well as 11 known compounds (4-14) were isolated from the fronds of Macaranga denticulata. Their structures were elucidated on the basis of extensive spectroscopic interpretation. Compounds 4 and 8 in...

The viscid exudate found on fronds o f the fern, Cheilanthes kaulfussii, consists of terpenoids in which flavonoid aglycones are dissolved. One of the terpenes is shown to be em-kaur-16-en-19-oic acid. The farinose frond exudate of Notholaena pallens contains this acid as the major constituent and its 3 /?-hydroxy derivative, together with flavonoid aglycones as minor components. In N. incana, ...

Objective: To evaluate the alpha amylase inhibitory activity of different extract of bark of Albizia lebbeck (L.) Benth. Methods: Bark of A. lebbeck was collected and air dried. Extraction of flavonoid, alkaloid and steroid carried out using standard methods. Extracts in different polar and non polar solvents were extracted using soxhlet method. Filtered extracts were subsequently tested for al...

The synthetic flavonoid EMD-49209 is a potent inhibitor of the in vivo and in vitro binding of thyroxine (T4) to transthyretin (TTR). We studied the distribution of125I-labeled EMD-49209 in maternal tissues, intestinal contents, and fetal tissues in rats that were 20 days pregnant (from 1 to 24 h after intravenous injection). The percent dose of EMD decreased quickly with time. In maternal brai...

'Huangjinya' is an excellent albino tea germplasm cultivated in China because of its bright color and high amino acid content. It is light sensitive, with yellow leaves under intense light while green leaves under weak light. As well, the flavonoid and carotenoid levels increased after moderate shading treatment. However, the mechanism underlying this interesting phenomenon remains unclear. In ...

Flavonoids, a group of phenolic compounds found in fruits and vegetables, are known to have antioxidant properties. They prevent low density lipoprotein oxidation in vitro and thus may play a role in the prevention of coronary heart disease (CHD). In 1986, in a prospective study of 34,492 postmenopausal women in Iowa, the authors examined the association of flavonoid intake with CHD and stroke ...

Flavonoids are exploited as antioxidants, antimicrobial, antithrombogenic, antiviral, and antihypercholesterolemic agents. Normally, conventional extraction techniques like soxhlet or shake flask methods provide low yield of flavonoids with structural loss, and thereby, these techniques may be considered as inefficient. In this regard, an attempt was made to optimize the flavonoid extraction us...