Morinda citrifolia is a member of the Rubiaceae. It is a Shrub or compacted to twisted small tree up to 8 m high with square stems and large stipules between nodes and petioles. Leaves are opposite, petiolate, glossy, mostly ovate, 15-35 cm long. Flowers white, up to 15 mm long, with a tubular corolla and 5 spreading lobes, the flowers borne on a globose syncarp. Fruit a large fleshy syncarp up...

P a t i e n t s 3510 patients who were ≥ 18 years of age (mean age 47 y, 57% men), had endoscopically confirmed erosive esophagitis ≥ grade 2, and had had ≥ 1 episode of moderate-tovery-severe heartburn during the previous 3 days or nights, or both. Exclusion criteria included duodenal or gastric ulcers ≥ 3 mm in diameter; systemic disease affecting the esophagus; history of gastrointestinal bl...

Disubstituted imidazoles were prepared by reacting appropriate phenylglyoxal with different aryl aldehydes in the presence of ammonium acetate. Trisubstituted imidazoles were prepared by reacting disubstituted imidazoles with chlorobenzene in the presence of catalytic amount of triethylamine (TEA). The synthesized compounds were characterized on the basis of IR, 1H-NMR and mass spectral data an...

Acute upper gastrointestinal bleeding is a common medical emergency around the world and the major cause is peptic ulcer bleeding. Endoscopic treatment is fundamental for the management of peptic ulcer bleeding. Despite recent advances in endoscopic treatment, mortality from peptic ulcer bleeding has still remained high. This is because the disease often occurs in elderly patients with frequent...

The synthesis of hydroxy benzophenones and benzophenone-N-ethyl morpholine ethers and the results of anti-inflammatory activity in vivo are described. The structures of the compounds were elucidated by IR, (1)H-NMR, mass spectroscopy and the elementary analysis. The anti-inflammatory activity of the synthesized compounds were determined by carrageenan-induced hind paw oedema test in rats. Most ...

In this experimental study of 65 ulcer patients and 25 healthy persons of this locality revealed an affinity of rice with ulceration. Experimental study conducted on 32 albino rats also confirmed the ulcerogenic property of rice. Arahara (red gram, Cojanus Ccaja) and to some extent wheat were found protective against peptic ulcer probably because of their high mucin output. Therefore, the study...

In this study, the anti ulcerogenic effect of water extract obtained from the leaves of Pueraria Tuberosa[PT] was investigated using cold restraint stress(CRU), pyloric ligation(PL) & Ethanol induced (EtOH) induced gastric ulcer models in rats. The treatment with PT at higher dose significantly inhibited gastric lesions induced by CRU (76.6%), PL (80.1%) & EtOH (70.6%) respectively with equal p...