The authors describe a case of histiocyte-rich B-cell lymphoma (HR-BCL), a variant of diffuse large B-cell lymphoma, in a 51-year-old man. The patient presented with large axillary lymphadenopathy. Histopathologic and immunohistochemical examination of lymph node biopsy revealed diffuse effacement of the lymph node architecture by reactive histiocytes and neoplastic CD20 positive B cells. ...

introduction: htlv-1 , the first known human retrovirus belongs to oncovirus subfamily of retroviruses. the major characteristic of htlv-1 is its highly restricted geographic prevalence. northern part of khorasan is an endemic region of htlv-1 infection. epidemiological studies can help in designing preventive programs for htlv-1 infection. the aim of this study was the establishment of a pcr t...

background: in this study we evaluated the prognostic impact of metastatic lymph node ratio (mlr) in patients with gastric cancer undergoing curative surgical resection. methods: a total of 121 patients with gastric adenocarcinoma undergoing curative r0 surgical resection in our institutions between 2003 and 2010 were included in this study.  mlr was classified into 3 groups as follows: mlr0; 0...

PURPOSE To investigate the effects of lymph node metastasis, skip metastasis, and other factors related to lymph node status on survival in patients who underwent radical cystectomy (RC) and extended lymph node dissection (eLND). MATERIALS AND METHODS RC and eLND were performed in 85 patients with a diagnosis of bladder cancer. Disease-free survival (DFS) and overall survival (OS) were determ...

BACKGROUND Margin status is the main factor determining local recurrence (LR) after wide excision and radiotherapy for breast cancer. The aim of the study is to evaluate if positive margins are as great a risk factor for LR in node-positive as in node-negative patients, since the major risk in the former group is dissemination and whether there is a correlation between nodal status and margins ...

Few long-term follow-up studies prove sentinel lymph node biopsy (SLNB) effectively stages breast cancer without the further evaluation of a completion axillary dissection. Our prospective study addressed this issue, enrolling 345 women with clinically node-negative breast cancer who underwent SLNB from October 1997 through December 2000. The median age of the patients in the study was 56.7 yea...

Background & Aims: Health related quality of life is one of the important concepts that nowadays is considered along with other quantitative criteria like life expectancy and survival in health service systems, but its significance is more obvious in degenerative diseases and long term treatments such as cancers. In this study we compared health related quality of life in breast cancer patients...