Within the color dipole gBFKL dynamics applied to the diffraction slope, we predict an anomalous t dependence of the differential cross section as a function of energy and Q for production of radially excited V ′(2S) light vector mesons in contradiction with a well known standard monotonous tbehaviour for V (1S) mesons. The origin of this phenomenon is based on the interplay of the nodal struct...

Nodal activity in the left lateral plate mesoderm (LPM) is required to activate left-sided Nodal signaling in the epithalamic region of the zebrafish forebrain. Epithalamic Nodal signaling subsequently determines the laterality of neuroanatomical asymmetries. We show that overactivation of Wnt/Axin1/beta-catenin signaling during late gastrulation leads to bilateral epithalamic expression of Nod...

We demonstrated previously that the activation of ALK7 (activin receptor-like kinase-7), a member of the type I receptor serine/threonine kinases of the TGF-β superfamily, resulted in increased apoptosis and reduced proliferation through suppression of Akt signaling and the activation of Smad2-dependent signaling pathway in pancreatic β-cells. Here, we show that Nodal activates ALK7 signaling a...

Nodal signaling induces the formation of the endoderm and mesoderm during gastrulation. Nodal expression persists until the definitive endoderm progenitor has completely formed, and disappears thereafter. A tightly regulated Nodal expression system is essential for the differentiation of embryonic stem (ES) cells into distinct tissue lineages. On this basis, we established an ES cell differenti...

observed that the sinus wave reached the AV node with a Introduction Atrioventricular septal defect (AVSD) can be associated with supraventricular arrhythmias and atrial fibrillation (AF). The position of the conduction system differs from the normal heart: the atrioventricular (AV) node is more posterior and inferior compared with the normal position in the triangle of Koch, in close relation ...

Effect of phase fluctuations on superconducting states with anisotropic order parameters is studied in a BCS like lattice model of cuprate superconductors. The degradation of the mean field transition temperature due to phase fluctuations is estimated within a Kosterlitz-Thouless scenario. Values of the interaction parameters for optimal doping, corresponding to a stable superconducting state o...

In this paper, we used a neutron diffusion hybrid equation with an external neutron source to calculate nuclear power factors in each fuel element in the reactor core. We used the nodal expansion method to obtain the neutron flux for a given control rods bank position. The results were compared with results obtained for eigenvalue problem near criticality condition and fixed source problem duri...

The geometric errors in the manufacturing process can be reduced by optimal positioning of the fixture elements in the fixture to make the workpiece stiff. We propose a new fixture layout optimization method N-3-2-1 for large metal sheets in this paper that combines the genetic algorithm and finite element analysis. The objective function in this method is to minimize the sum of the nodal defle...

We have raised a mouse monoclonal antibody that reacts specifically with the myocytes of the sinoatrial node of the bovine heart. By use of this antibody (445-6E10) and antibodies against the gap junction protein connexin43, the periphery of the sinoatrial node and the distribution of gap junctions in the nodal region were studied. The reaction patterns of 445-6E10 and anti-connexin43 are exact...

During early zebrafish development the nodal signalling pathway patterns the embryo into three germ layers, in part by inducing the expression of no tail (ntl), which is essential for correct mesoderm formation. When nodal signalling is inhibited ntl fails to be expressed in the dorsal margin, but ventral ntl expression is unaffected. These observations indicate that ntl transcription is under ...