Fungal keratitis (FK) is a corneal infection caused by different fungal species. It treated the topical application of natamycin (NAT). Nevertheless, this approach faces many limitations like toxic effects, frequent dosing, resistance, and patient discomfort. The present research reports development trimethyl chitosan (TMC) coated mucoadhesive cationic niosomes modified thin-film hydration meth...

The turn of century has witnessed a huge increase in the number of technologies and immunological approaches for new vaccine design. Vesicular carriers, i.e. liposomes, niosomes, transfersomes represent widely exploited class of novel delivery systems for topical applications. Non-invasive vaccination onto the skin using these novel carriers could improve vaccination programs because the proced...

This study aims to investigate the capability of forming itraconazole containing niosomes with Span 60 and Brij 58 as non-ionic surfactants. Lower cost and higher stability makes niosomes a more suitable choice in comparison with liposomes.The capability to form vesicles as an itraconazole delivery system and the influence of different factors such as type of surfactant and molar ratio of chole...

Over the last few years an inclusive research has been done over provesicular approach for transdermal drug delivery. Skin has a very tough diffusion barrier inhibiting penetration of drug moiety which is rate limiting barrier for penetration of drugs. There are several approaches that deal with penetration enhancement across the skin. Vesicular and provesicular systems are promising amongst th...

Niosomes are nonionic surfactant vesicles that have potential applications in the delivery of hydrophobic and hydrophilic drugs. Permeation of a potent nonsteroidal anti-inflammatory, ketorolac, across excised rabbit skin from various proniosome gel formulations was investigated using Franz diffusion cells. Each of the prepared proniosomes significantly improved drug permeation and reduced the ...