OBJECTIVE To study the effects of two, months Nigella sativa (N. sativa) oral supplementation to normal rats on cardiac haemodynamics in vivo, the ionotropic and chronotropic properties of the isolated hearts in vitro, and the cardiac responsiveness to progressive adrenergic stimulation by isoproterenol. METHODS The cardiac workload, after 2 months of N. sativa oral supplementation to normal ...

The anti-ischemic effect of aqueous and ethanolic extracts of Nigella sativa L. seed was studied using a four-vessel occlusion model in rats. The ischemia was evaluated by optical and transmission electron microscopy. After 20 min of forebrain ischemia, agents were administered intraperitoneally after reperfusion. Both extracts comprised an alkaloid. In ischemic rats, the aqueous (1 g/kg) and e...

BACKGROUND Thymoquinone is the major active principle of Nigella sativa (N. sativa) and constitutes about 30% of its volatile oil or ether extract. N. sativa oil and seed are commonly used as a natural remedy for many ailments. Using modern scientific techniques, a number of pharmacological actions of N. sativa have been investigated including immunostimulant, anti-inflammatory, anticancer, ant...

conclusions: nigella sativa oil and fish oil were effective in reduction the size of patient’s lesions; however, nigella sativa was more effective in comparison to the fish oil. therefore, using nigella sativa with the major drugs in the treatment of vitiligo is recommended. background: vitiligo is one of the autoimmune skin diseases that destroy the melanocytes of the skin. moreover, its preva...

Backgound: The major obstacle limiting the use of aminoglycoside, antibiotics has been and continues to be the possibility of drug induced ototoxicity and nephrotoxicity. Study dsign: Changes in biochemical parameters related to nephropathy before and after of nigella sativa were observed. Material and methods: Ten rabbits were included in the study, comprised as group 1 and 11. Group I was onl...

BACKGROUND Nigella sativa (black cumin) and Cinnamomum cassia (Cinnamon) are an integral part of the Indian diet, and have also been sourced in the ayurveda, the traditional Indian system of medicine, for their medicinal properties. Both the herbs individually have been successfully evaluated for their preliminary antidiabetic potential. OBJECTIVE Herein, we dived deeper into antidiabetic pro...

Acoustic trauma is a common reason for hearing loss. Different agents are used to prevent the harmful effect of acoustic trauma on hearing. The aim of this study was to evaluate the potential preventive effect of Nigella sativa (black cumin) oil in acoustic trauma. Our experimental study was conducted with 20 Sprague Downey female rats (mean age, 12 months; mean weight 250 g). All of the proced...

In a sustainable agriculture system, application of the fertilizers which are nature friendly and suitable for plants is essential. This becomes more important when dealing with medicinal plants. Therefore, a factorial experiment in a randomized complete block design with three replications was set up in the 2012-2013 on Nigella sativa L. Treatments were nano­fertilizer (Pharmks®) (at 2 levels ...