Avirulent (lentogenic) strains of Newcastle disease virus form plaques on chicken embryo lung monolayers in 48 to 72 h.

Prolonged treatment with relatively high concentrations of interferon was required to "cure" L cells persistently infected with Newcastle disease virus.

newcastle disease virus (ndv) is known as one of the most important endemic viral pathogen for various avian species such as ostrich, in iran. therefore, establishing a routine vaccination program against nd in ostrich flocks would be useful in order to reduce the danger of this infection. newcastle disease occurs among the ostriches and leads to high rate of mortality while most of the losses ...

Bolognesi, D. P. (Rensselaer Polytechnic Institute, Troy, N.Y.), and D. E. Wilson. Inhibitory proteins in the Newcastle disease virus-induced suppression of cell protein synthesis. J. Bacteriol. 91:1896-1901. 1966.-Infection by Newcastle disease virus brings about a rapid and marked inhibition of cell protein synthesis (CPS) in chick embryo fibroblast monolayers. The block to CPS is initiated a...

Newcastle disease (ND) is one of the most important diseases of poultry, negatively affecting poultry production worldwide. The disease is caused by Newcastle disease virus (NDV) or avian paramyxovirus type 1 (APMV-1), a negative-sense single-stranded RNA virus of the genus Avulavirus, family Paramyxoviridae. Although all NDV isolates characterized to date belong to a single serotype of APMV-1,...

Newcastle disease (ND) is one of the most serious illnesses of chickens. Live vaccines are widely used to prevent chicken from the disease all over the world. To access the effective and potentiate ND vaccine, a homogenous subpopulation from LaSota strain was selected following cultivation of the virus on primary chicken embryofibroblast (CEF) cells. Pathogenicity indices and molecular characte...

We report the complete genomic sequence of a novel Newcastle disease virus (NDV) strain, duck/China/Guangxi19/2011, isolated from a white duck in Guangxi Province, southern China. Phylogenetic analysis based on a fusion gene comparison with different NDV strains revealed that duck/China/Guangxi19/2011 is phylogenetically close to genotype IX NDV, and the deduced amino acid sequence of the fusio...

This report describes an attempt to define the factors which incite secondary bacterial pneumonias. Groups of mice were given bacteria intraperitoneally and, at various intervals, Newcastle disease virus intravenously. There was an increase in the number of deaths and in the rates of death in these groups, when compared with a control group which was given only bacteria. These results were obta...

The phosphoprotein, or P protein, of Newcastle disease virus is required for transcription of the viral genome (1) and is the major product of the P gene (2). The cDNA for the complete P gene of Newcastle disease virus (strain Beaudette C) was cloned and sequenced in both directions by using Bal-3 1 and restriction endonuclease subcloning. The largest open reading frame of the P gene codes for ...