objectives the current research aimed to study achillea millefolium and thymus vulgaris antiviral activity against newcastle disease virus (ndv). materials and methods the antiviral activity of the plants was measured by the reduction assay of viral titer, and explained by inhibition percentage (ip). background nowadays natural products such as pure compounds and plant extract scan provide unli...

In the present study, 360 male day-old broiler chicks were used to determine the effect of mixed livevaccines of Newcastle disease (ND) and infectious bronchitis (IB) on serum and local antibody responses toIB. Chicks were randomly divided into 12 treatment groups of 3 replicates and reared for 40 days on floorpens. Groups 1 to 5 received mixed ND and IB vaccine. Groups 7 to 11 received IB vacc...

Newcastle disease (ND) remains a constant threat to poultry producers worldwide, in spite of the availability and global employment of ND vaccinations since the 1950s. Strains of Newcastle disease virus (NDV) belong to the order Mononegavirales, family Paramyxoviridae, and genus Avulavirus, are contained in one serotype and are also known as avian paramyxovirus serotype-1 (APMV-1). They are ple...

Five commercial LaSota strain Newcastle disease (ND) vaccines namely A, B, C, D and E were evaluated for their potency, efficacy, thermostability and influence on productivity in broilers. A 3-log10 difference of EID50 and two-to-eight fold difference of HA activity was found among the various vaccines tested. One hundred and fifty day-old broiler chicks were divided into six equal groups tagge...

Virulent strains of Newcastle disease virus (NDV) can cause devastating disease in chickens worldwide. Although the current vaccines are substantially effective, they do not completely prevent infection, virus shedding and disease. To produce genotype-matched vaccines, a full-genome reverse genetics system has been used to generate a recombinant virus in which the F protein cleavage site has be...

Newcastle disease is one of the most important diseases of poultry. It usually causes a great loss inpoultry industry and domestic village chickens. Since domestic chickens in villages are free ranging for food,the chance of their contact with wild birds that may act as reservoirs is high. To determine the role ofdomestic chickens in the epizootiology of Newcastle disease virus in villages of I...

During 2002-2003, exotic Newcastle disease (END) virus caused a major outbreak among commercial and backyard poultry in southern California and adjacent states. The outbreak raised concerns regarding the protective immunity of commercially available vaccines for prevention and control of this virus in poultry. We sought to determine if existing commercial live and inactivated Newcastle disease ...