Gorlin-Goltz syndrome, or nevoid basal cell carcinoma syndrome (NBCCS), is a rare autosomal dominant disorder caused by mutations in the PTCH1 gene and shows a high level of penetrance and variable expressivity. The syndrome is characterized by developmental abnormalities or neoplasms and is diagnosed with 2 major criteria, or with 1 major and 2 minor criteria. Here, we report a new clinical ma...

background:non-melanoma skin cancer (nmsc), the most prevalent types being squamous cell carcinoma (scc) and basal cell carcinoma (bcc), is the most common type of malignancy in human beings. these neoplasms are more frequent in the elderly and fair skinned people and mainly occur on sun-exposed sites of the body. ultraviolet b (uvb) has a well-known effect in induction and promotion of growth ...

background and aim: basal cell carcinoma (bcc) is the most common skin neoplasm and the most common type of cancer. since the incidence of injury is taken into consideration in the pathologic diagnosis, the study of clinical and microscopic views of bcc is of particular importance. the present study aimed at determining the frequency of clinical and microscopic views of bcc in a 10-year period ...

skin cancer has a broad and burdensome impact on the health and well-being of iranian and account for substantial health care costs to the nation. the first most common form of skin cancer is basal cell carcinoma (bcc); followed by the squamous cell carcinoma (scc) and the incidence of malignant melanoma (mm) is lower but is fatal. kaposi sarcoma (ks) is a tumor caused by human herpes virus 8. ...

background and objective: basal cell carcinoma (bcc) and squamous cell carcinoma (scc) are two common tumors of the skin. in some cases, distinction between bcc and scc can be difficult. this study aimed to clarify this uncertainty through immunohistochemical analysis. in this respect, epithelial membrane antigen (ema) and ber-ep4 are the two immunohistochemical markers on which we focus in dif...