Introduction The delivery of electrodes or other therapeutic agents to the brain frequently requires precision minimally invasive access. MR is ideally suited to this application and high targeting accuracies have been reported when delivering deep brain stimulator (DBS) electrodes (1). Convection enhanced delivery (CED) is a promising technique for delivering drug and gene therapies to the bra...

Definition and history Inflammation of the brain can be caused by a number of diseases, but one of the preventable causes is viral infection. In addition to Rabies, with which most people have some familiarity, two other families of virus can cause brain infections in horses, resulting in what is commonly termed viral encephalitis. The first and older group is the Alphavirus family (previously ...

P rimary angiitis of the central nervous system (PACNS) is a rare form of vasculitis of unknown cause. The mean age of onset is 50 years, and men are affected twice as often as women. Headache and encephalopathy are the most frequent initial symptoms. Stroke or focal symptoms develop in less than 20% of patients at the onset of disease and are uncommon in the absence of headache or encephalopat...

The effectiveness of noninvasive treatment for neurological disease is generally limited by the poor entry of therapeutic agents into the central nervous system (CNS). Most CNS drugs cannot permeate into the brain parenchyma because of the blood-brain barrier thus, overcoming this problem has become one of the most significant challenges in the development of neurological therapeutics. Nanotech...

 Abstract Background: Mustard gas, lethal in high doses, affects multiple organs such as skin, eye and respiratory system. We studied the development of late onset mustardinduced polyneuropathy among chemically wounded Iranian veterans. Methods: In this descriptive study, 100 chemically wounded Iranian veterans with severe eye involvement were examined for any signs and symptoms of polyneuropat...

Based upon a thorough review of published clinical observations regarding the inhibitory system, I hypothesize that this system may play a key role in the pathogenesis of a variety of neuromuscular and neurological diseases. Specifically, excitatory overstimulation, which is commonly reported in neuromuscular and neurological diseases, may be a homeostatic response to inhibitory overstimulation...

The paper presents a new, experimental, wireless tremor telemonitoring system composed of an optional variable number of portable devices integrating three-axis acceleration mini-sensors which are connected to very small dimensions acquisition systems with Wi-Fi transmission capabilities. The main advantages of the design system consist of the possibilities to monitor simultaneously many body p...