PURPOSE OF REVIEW Almost 100 years after its original description, sarcoidosis remains an enigmatic disease with unclear etiology and capricious symptomology, as well as a diagnostic challenge. This review coalesces current literature on the neuro-ophthalmic manifestations of sarcoidosis and discusses the epidemiology, etiology, clinical presentation, diagnosis, and management of this disease. ...

Behcet disease is a rare multi-system immune related vasculitis which may involve the central nervous system, usually during the course of the illness. Magnetic resonance imaging is currently the modality of choice for the detection of the parenchymal lesions in their different phases, as well as the dural sinus venous thrombosis.

Brucellosis is an endemic zoonotic infectious disease in Middle East countries including Iran. This infection may involve central nervous system. Psychosis has been reported in rare cases with chronic brucellosis.A 26-year-old male shepherd patient who developed neuro-brucellosis and psychosis is presented. He had hallucinations (visual and auditory) and delusions. He was also impulsive and had...

For neuro-oncologists, much was accomplished in the last decade, including the establishment of the first standard of care (SOC) in this field of oncology. New treatment options boosted research in the whole field of neuro-oncology, as well clinical trials, translational and basic research. Accumulated data on molecular-genetic subgroups with distinct clinical outcomes in disease entities led t...