PURPOSE: Two-stage facial reanimation procedures with a cross-facial nerve graft often yield less predictable results in older patients due to multifactorial reasons. Some studies strongly suggest that increased donor nerve axonal load improves function of a free muscle transfer after a crossfacial nerve graft. However, strong studies characterizing the relationship between age and facial nerve...

Concepts of neuronal damage and repair date back to ancient times. The research in this topic has been growing ever since and numerous nerve repair techniques have evolved throughout the years. Due to our greater understanding of nerve injuries and repair we now distinguish between central and peripheral nervous system. In this review, we have chosen to concentrate on peripheral nerve injuries ...

BACKGROUND Ansa cervicalis (AC)-recurrent laryngeal nerve anastomosis (RLN) is usually not desirable for correction of paralytic dysphonia when it is difficult to find a viable distal stump of the recurrent laryngeal nerve. Nerve implantation of the thyroarytenoid muscle with the ansa cervicalis is a simple alternative method. STUDY DESIGN Ten patients with unilateral vocal cord paralysis wer...

Results The number of operative cases of brachial plexus injury increase each year. Fifty nine percent of cases were managed in public hospitals and 41% in private hospitals. Most of the patients were males (86%) and the rest were females (14%). Brachial plexus injury was most prevalent between 21-30 years of age (37%). Motor vehicle accident was the most frequent mode of injury (90%). The righ...

Recently, we showed that Schwann cells transfer ribosomes to injured axons. Here, we demonstrate that Schwann cells transfer ribosomes to regenerating axons in vivo. For this, we used lentiviral vector-mediated expression of ribosomal protein L4 and eGFP to label ribosomes in Schwann cells. Two approaches were followed. First, we transduced Schwann cells in vivo in the distal trunk of the sciat...

The utilization of nerve transfer procedures in the upper extremity following brachial plexus injury, trauma, spinal cord tumors, infection or other etiologies are well established. Nerve injuries lower pose several additional challenges, including longer distance to target motor end plates, far-proximal lumbar pelvis, delayed presentation, and concomitant limb trauma. transfers have potential ...

IMPORTANCE Reconstruction of the facial nerve after radical parotidectomy is commonly performed with cable grafting, which is associated with slow recovery of nerve function and synkinesis. OBJECTIVE To describe facial nerve reconstruction after radical parotidectomy using concurrent masseteric nerve transfer and cable grafting. DESIGN, SETTING, AND PARTICIPANTS This retrospective medical r...

BACKGROUND Lesions in peripheral nerves are highly prevalent in the upper extremity. The present study compares different tendon transfer surgeries in patients with radial nerve palsy. METHODS Fifty patients with radial nerve palsy were randomly selected among patients who referred to Tehran 15(th) Khordad Hospital during 2006-2011. They were divided into two groups of 17 and 33 subjects. Sin...

OBJECTIVE To demonstrate the new sensory restoration technique in radial nerve injury using the first branch of dorsal ulnar cutaneous nerve as the donor sensory nerve. MATERIAL AND METHOD Forty formalin-preserved cadavers (18 males and 22 females) were used as the subjects of the present study. The localization of the origin of first branch of dorsal ulnar cutaneous nerve was performed. The ...