Functional recovery is often unsatisfactory after severe extended nerve defects or proximal nerve trunks injuries repaired by traditional repair methods, as the long regeneration distance for the regenerated axons to reinnervate their original target end-organs. The proximal nerve stump can regenerate with many collaterals that reinnervate the distal stump after peripheral nerve injury, it may ...

ReSultS: Of 818 residents, a minority were integrated (35.7%) relative to independent (64.3%). During several years, integrated residents performed more procedures in hand reconstruction, congenital deformity, tendon repair, nerve repair, nerve decompression, amputation, arterial repair, and Dupuytren’s release categories (p < 0.05). There were no significant changes in fold differences between...

Phrenic nerve transfer is a major dynamic treatment used to repair brachial plexus root avulsion. We analyzed 72 relevant articles on phrenic nerve transfer to repair injured brachial plexus that were indexed by Science Citation Index. The keywords searched were brachial plexus injury, phrenic nerve, repair, surgery, protection, nerve transfer, and nerve graft. In addition, we performed neuroph...

The end-to-side nerve-repair technique, i.e., when the distal end of an injured nerve is attached end-to-side to an intact nerve trunk in an attempt to attract nerve fibers by collateral sprouting, has been used clinically. The technique has, however, been questioned. The aim of the present study was to investigate end-to-side repair in the upper extremity of rats with emphasis on functional re...

Sensory or motor "baby-sitting" has been proposed as a clinical strategy to preserve muscle integrity if motion-specific axons must regenerate over a long distance to reach denervated target muscles. Denervated muscles are innervated temporarily by using axons from nearby sensory or motor nerves. After motion specific motor axons have reached the target, the baby-sitter nerve is severed and mot...

ReSultS: Of 818 residents, a minority were integrated (35.7%) relative to independent (64.3%). During several years, integrated residents performed more procedures in hand reconstruction, congenital deformity, tendon repair, nerve repair, nerve decompression, amputation, arterial repair, and Dupuytren’s release categories (p < 0.05). There were no significant changes in fold differences between...

Prevention of the atrophy of denervated muscles is essential for a good outcome in facial contouring and oral reconstruction. In this study, we compared the effectiveness of end-to-end and end-to-side neurorrhaphy of the motor nerve, and end-to-end neurorrhaphy of the sensory nerve, all of which are frequently used in such reconstruction for the prevention of muscle atrophy. Wistar rats were di...

Background: This study aimed to introduce a modified technique for minimally invasive Achilles tendon (AT) rupture repairusing gift box sutures. The preliminary clinical and functional outcomes were investigated among a number of patients.Methods: In a consecutive case series study, 24 patients with acute AT rupture underwent modified minimally invasiveAT repair using two mini...

Objective-Effect of local administration of laminin and fibronectin on nerve regeneration was assessed. Design- Experimental study. Animal- Sixty male Wistar rats. Procedures- The animals were divided into four experimental groups (n=15), randomly: In transected group left sciatic nerve was transected and stumps were fixed in adjacent muscle. In treatment group (CHIT/LF) the defect was bridg...

Cell membrane has a critical and vital role in functioning and existence of nerve cells that form central nervous system (CNS) in mammals. Disruption of nerve membrane that normally occurs following an accident injuring spinal cord is known to be the major cause of paralysis. In most occasions, spinal cord injuries are not leading to complete cut in spinal cord fibers but are known to cause cru...