Despite the advances in perinatal and neonatal care and use of newer potent antibiotics, the incidence of neonatal sepsis remains high and the outcome is still severe. For years, investigators have sought a test or panel of tests able to identify septic neonates accurately and rapidly in order to obtain an early diagnosis and develop a specific effective treatment for a successful outcome. In a...

Introduction: Evaluation of the cerebrospinal fluid (CSF) white blood cell (WBC) count and glucose and protein concentrations is used to assess the probability of the presence of central nervous system (CNS) infection. Although normal values are well established for CSF cell counts and protein and glucose contents in children and adults, this is not the case for neonates. The purpose of this st...

Despite the advances in perinatal and neonatal care and use of newer potent antibiotics, the incidence of neonatal sepsis remains high and the outcome is still severe. For years, investigators have sought a test or panel of tests able to identify septic neonates accurately and rapidly in order to obtain an early diagnosis and develop a specific effective treatment for a successful outcome. In a...

Acute neonatal posterior fossa subdural hematoma has been documented 13 times since 1940. Typically it occurs in a full-term infant whose delivery is complicated by forceps extraction or breech delivery. Lethargy, irritability, and respiratory irregularities occur within the first few days of life. Tense anterior fontanels and increasing head circumference result from progressive hydrocephalus....

Disturbed sleep during affective episodes may impact levels of cerebrospinal fluid (CSF)-amyloid-beta (Aβ)42 and other biomarkers neurodegeneration in patients with bipolar disorder (BD). The study aimed to investigate the correlations between for Alzheimer's disease (AD) BD healthy controls (HC). We present a prospective, longitudinal case-control euthymic (N = 86) HC 44). All participants wer...

INTRODUCTION Elizabethkingia meningoseptica is a rare but well-recognised cause of neonatal meningitis. Reported outbreaks have involved very few cases. We describe the management and outcome of a relatively large outbreak of E.meningoseptica neonatal meningitis METHODOLOGY From August 2002 to December 2003, eight cases of meningitis caused by E. meningoseptica occurred among babies admitted ...