Neisseria meningitidis is a facultative pathogen bacterium which is well founded with a number of adhesion molecules to facilitate its colonization in human nasopharynx track. Neisseria meningitidis is a major cause of mortality from sever meningococcal disease and septicemia. The Neisseria meningitidis adhesion, NadA, is a trimeric autotransporter adhesion molecule which is involved in cell ad...

Worldwide Chlamydia trachomatis and Neisseria gonorrhoeae are two of the most prevalent sexually transmitted pathogens. The present study aimed to estimate the prevalence of Chlamydia trachomatis and Neisseria gonorrhoeae infection in women from Taif, western region, KSA. A polymerase chain reaction (PCR) method was carried using DNA extracted from 144 female urine samples. Primer pairs specifi...

Bacteriocin typing has been described previously and proposed for typing gonococci. A survey has been made of 150 strains of N. gonorrhoeae from various places to determine the feasibility of a gonocin typing system. All strains were found to produce an inhibitory substance which inhibited all strains of gonococci tested, one strain of Neisseria flavescens, two strains of Neisseria meningitidis...

to evaluate the effect of intrauterine cephapirin on treatment of endometritis 39 holstein dairy cows that affected with postpartum endometritis were selected and randomly assigned to two experimental designs. in experiment 1, 6 out of 14 cows were 25 to 30 days after parturition were treated by intrauterine oxytetracycline. another 8 cows were treated by intrauterine cephapirin (metri-care). i...

background and aims. reactive hyperplasias (rhs) are common oral mucosal lesions caused by irritation of the mu-cosa. the aim of this study was to evaluate the frequencies of various types of oral rhs in a university clinic. materials and methods. oral rh cases, undergone biopsy in a four-year period, were studied retrospectively. data including age and gender as well as the location and clinic...

Neisseria meningitidis N. meningitidis, or meningococcus, is an aerobic, gramnegative diplococcus, closely related to N. gonorrhoeae, and to several nonpathogenic Neisseria species, such as N. lactamica. The organism has both an inner (cytoplasmic) and outer membrane, separated by a cell wall. The outer membrane contains several protein structures that enable the bacteria to interact with the h...

Neisseria gonorrhoeae is one of the leading antimicrobial resistance threats worldwide. This study determined the MICs of closthioamide to be 0.008 to 0.5 mg/liter for clinical N. gonorrhoeae strains and related species. Cross-resistance with existing antimicrobial resistance was not detected, indicating that closthioamide could be used to treat drug-resistant N. gonorrhoeae.

PCR-based assays for the identification of Neisseria meningitidis serogroups 29E, X, and Z by detection of specific regions of the ctrA gene are described. The specificities of these assays were confirmed using serogroups A, B, C, 29E, H, W135, X, Y, and Z and nongroupable meningococcal isolates.

UNLABELLED Neisseria meningitidis colonizes the nasopharyngeal mucosa of healthy populations asymptomatically, although the bacterial surface is rich in motifs that activate the host innate immunity. What determines the tolerant host response to this bacterium in asymptomatic carriers is poorly understood. We demonstrated that the conserved meningococcal surface protein NhhA orchestrates monocy...

Neisseria meningitidis colonizes the nasopharynx and, unlike commensal Neisseria species, is capable of entering the bloodstream, crossing the blood-brain barrier, and invading the meninges. The other pathogenic Neisseria species, Neisseria gonorrhoeae, generally causes an infection which is localized to the genitourinary tract. In order to investigate the genetic basis of this difference in di...