This report describes a previously unrecognized role for bacterial surface layers as barriers that confer protection against antimicrobial peptides. As antimicrobial peptides exist in natural environments, S-layers may provide a bacterial survival mechanism that has been selected for through evolution.

The antimicrobial activity of fifteen semisynthetic labdane-type diterpenes derived from the two major natural compounds 3 and 4 of the resin "ladano" of Cistus creticus is reported. The chloroethyl carbamidic esters 15 and 20 showed the strongest antimicrobial activity against Gram(+), Gram(-) bacteria and pathogenic fungi.

The objectives of this research were to validate the sensitivity and precision of an in vitro assay for evaluating the efficacy of antimicrobials, to evaluate the ability of natural animal proteins/peptides to kill in vitro antibiotic-resistant, as well as, -susceptible bacteria, and to determine the effects of key components of animal digesta (e.g., pH, mineral content, and proteolytic digesti...

The increasing global public health concern of antimicrobial resistance (AMR) necessitates exploration of natural antimicrobial agents as potential alternatives. This study aims to investigate antimicrobial activities of Saharan actinomycetes, with specific focus on the strain Streptomyces fimbriatus AC31, that holds promising potential as an alternative to combat AMR. In this context, 32 actin...

Owing to its high biodegradability, and nontoxicity and antimicrobial properties, chitosan is widely-used as an antimicrobial agent either alone or blended with other natural polymers. To broaden chitosan's antimicrobial applicability, comprehensive knowledge of its activity is necessary. The paper reviews the current trend of investigation on antimicrobial activities of chitosan and its mode o...

Uropathogenic organisms have evolved numerous defense mechanisms against antimicrobial agents, hence resistance to old and newly available drugs are increasing at an unprecedented level. The events of antibiotic resistance have lead for screening of several medicinal plants for their potential antimicrobial activity. The aim of this study was to evaluate the antimicrobial efficacy of Cyminumcum...

background :    searching for the potent natural antibiotics will improve the treatment of most infectious diseases. cyclotides are potent active peptides derived from some plant families like violaceae. viola tricolor (the pansy) has been found to have numerous cyclotides. nowadays cyclotides attract more attention for their antibacterial activities.  the current research studied the antimicro...

There is a growing interest in food industry to replace the synthetic chemicals by the natural products with bioactive properties from plant origin. The aim of this study was to determine the chemical composition of Mentha pulegium essential oil and to characterize the antimicrobial activities of the essential oil. The essential oil of Mentha pulegium was analyzed by GC-MS. The evaluation of th...

Biopreservation or biocontrol refers to the use of natural or controlled microbiota, or its antibacterial products to extend the shelf life and enhance the safety of foods (Stiles 1996 ). Since lactic acid bacteria (LAB) occur naturally in many food systems and have a long history of safe use in fermented foods, thus classed as Generally Regarded As Safe (GRAS), they have a great potential for ...

Lactocin 160 is a vaginal probiotic-derived bacteriocin shown to selectively inhibit the growth of Gardenerella vaginalis and some other pathogens commonly associated with bacterial vaginosis. The natural origin of this peptide, its safety, and selective antimicrobial properties make it a promising candidate for successful treatment and prophylaxis of bacterial vaginosis (BV). This study evalua...