INTRODUCTION Scientific guidelines recommend the National Institutes of Health Stroke Scale (NIHSS) for ischemic stroke (IS) assessment. In Clinical Department of Neurology of Split University Hospital Center nurses use the categorization of patients (COP) according to individual needs for health care. AIM The aim of this study was to demonstrate that there is a positive correlation between t...

BACKGROUND AND PURPOSE Insulin-like growth factor I (IGF-I) is neuroprotective in animal models of stroke. We investigated whether serum IGF-I levels in patients with acute ischemic stroke influence stroke severity and outcome. METHODS Concentrations of IGF-I and IGF binding protein 3 were measured in serum samples obtained within 6 hours after stroke onset from 255 patients who took part in ...

BACKGROUND AND PURPOSE Our aim was to determine the relationships between angiographic collaterals and diffusion/perfusion findings, subsequent infarct growth, and clinical outcome in patients undergoing endovascular therapy for ischemic stroke. METHODS Sixty patients with a thrombolysis in cerebral infarction (TICI) score of 0 or 1 and internal carotid artery/M1 occlusion at baseline were ev...

In acute stroke care, time is brain, and the earlier thrombolysis is given the better the final functional outcome is. Our recently published single-center analysis showed robust benefit of ultra-early compared with later thrombolysis in terms of better outcome and lower mortality, outcomes supported by the most recently published pooled analysis. In our study, we identified 10% of patients wit...

BACKGROUND AND PURPOSE Risks and benefits of intravenous thrombolysis for patients with stroke > 80 years of age are unclear. We examined outcomes and symptomatic intracerebral hemorrhage rates in ≤ 80- and > 80-year-old patients in the Safe Implementation of Treatment in Stroke International Stroke Thrombolysis Register. METHODS We compared mortality and independence (modified Rankin Scale 0...

BACKGROUND AND PURPOSE It is unknown how little flow velocity improvement is necessary to achieve recanalization and clinical recovery. We sought to investigate which flow velocity parameter was associated with complete recanalization/reperfusion and neurological improvement in patients receiving reperfusion therapies. METHODS Patients with proximal intracranial occlusions were treated with s...

Background and Purpose—We sought to assess the psychometric attributes of the Brazilian version of the Stroke Impact Scale (SIS) 3.0 in stroke survivors. Methods—Patients were evaluated by the National Institutes of Health Stroke Scale, Mini-Mental State Examination, Barthel Index, Lawton Instrumental Activities of Daily Living Scale, modified Rankin Scale, Geriatric Depression Scale, and Hospi...