The deregulation of microRNAs (miRNAs) is involved in the development and progression of various types of human malignancy. Previously, it has been suggested that miR‑214 has an oncogenic role in nasopharyngeal carcinoma. However, the detailed molecular mechanisms remain to be elucidated. In the present study, reverse transcription‑quantitative polymerase chain reaction and western blot analysi...

Nasopharyngeal carcinomas (NPCs) have a particularly high risk for aggressive clinical behavior. Metastatic tumors or secondary malignant neoplasms to the breast are uncommon. Breast metastasis of NPCs is very rare. We report a case of NPC in a 17-year-old female patient presenting with a mass in her left breast. The tumor consisted of an inflammatory infiltrate rich in lymphoplasmacyticcells a...

Tuberculosis (TB) is a common infectious disease worldwide. It can affect many organs, the most common is lungs infection. Upper respiratory tract involvement is uncommon and the least common regional involvement is nasopharyngeal region. The authors report a case of nasopharyngeal tuberculosis who came with diplopia which is a very rare presentation. Nasopharyngeal tuberculosis is a rare condi...

BACKGROUND Although the prevalence of nasopharyngeal tuberculosis has decreased after the wide use of anti-tuberculous agents, recently the number of reports with the disease has slightly increased in accordance with advances in the diagnostic tools. A case of nasopharyngeal tuberculosis without any tuberculous lesions in other organs (primary nasopharyngeal tuberculosis) was reported. CASE R...

BACKGROUND Nasopharyngeal carcinoma often occurs in humans in the nasopharyngeal epithelium area. Ebstein-Barr (EB) virus plays a key role in the process of nasopharyngeal carcinoma lesions. Early antigen antibody (EA-IgA) and viral capsid antigen IgA (VCA-IgA) of EB virus detection in serum can effectively monitor the process of nasopharyngeal carcinoma lesions. Serum vascular endothelial grow...

BACKGROUND Circulating cell-free Epstein-Barr virus (EBV) DNA is a biomarker for nasopharyngeal carcinoma. We conducted a prospective study to investigate whether EBV DNA in plasma samples would be useful to screen for early nasopharyngeal carcinoma in asymptomatic persons. METHODS We analyzed EBV DNA in plasma specimens to screen participants who did not have symptoms of nasopharyngeal carci...

INTRODUCTION Acquired nasopharyngeal stenosis typically occurs as a result of surgery or irradiation of the nasopharynx. Sarcoidosis has numerous manifestations in the head and neck region, although an association with nasopharyngeal stenosis has not previously been reported. CASE REPORT A 40-year-old man with sarcoidosis developed severe acquired nasopharyngeal stenosis. This was successfull...

This report describes a case of cytomegalovirus (CMV) infection of the nasopharynx. A 47 year old man presented with a nasopharyngeal mass of one month's duration. The patient had a history of pneumonia one month previously. Sinus computed tomography incidentally picked up a nasopharyngeal mass. The initial biopsy showed lymphoid hyperplasia. Repeated nasopharyngoscopy showed a prominent centra...

BACKGROUND AND PURPOSE Our previous nasopharyngeal carcinoma detection study, comparing MR imaging, endoscopy, and endoscopic biopsy, showed that MR imaging is a highly sensitive test that identifies nasopharyngeal carcinomas missed by endoscopy. However, at the close of that study, patients without biopsy-proved nasopharyngeal carcinoma nevertheless had shown suspicious abnormalities on endosc...

AIMS AND BACKGROUND NYD-SP8 is a recently identified protein, the biological characteristics of which are still unclear. The aim of this study was to prepare an anti-NYD-SP8 rabbit polyclonal antibody and investigate the expression of NYD-SP8 in human nasopharyngeal carcinoma cell lines and nasopharyngeal carcinoma tissues. METHODS The anti-NYD-SP8 rabbit polyclonal antibody was prepared and ...