Patients with metastatic castration-resistant prostate cancer (mCRPC) have poor outcomes. Docetaxel (DTX)-based therapy is a current standard treatment for patients with mCRPC. Approaches combining conventional chemotherapeutic agents and nanoparticles (NPs), particularly iron oxide NPs, may overcome the serious side effects and drug resistance, resulting in the establishment of new therapeutic...

The development of noninvasive imaging techniques for the accurate diagnosis of progressive hepatocellular carcinoma (HCC) is of great clinical significance and has always been desired. Herein, a hepatocellular carcinoma cell-targeting fluorescent magnetic nanoparticle (NP) was obtained by conjugating near-infrared fluorescence to the surface of Fe3O4 (NIRF-Fe3O4) NPs, followed by coating the l...

Docetaxel (DTX) is one of the most important anticancer drugs; however, the severity of its adverse effects detracts from its practical use in the clinic. Magnetic nanoparticles of Fe3O4 (MgNPs-Fe3O4) can enhance the delivery and efficacy of anticancer drugs. We investigated the effects of MgNPs-Fe3O4 or DTX alone, and in combination with prostate cancer cell growth in vitro, as well as with th...

Acrylic acid and styrene were polymerized onto monodispersed Fe3O4 nanoparticles using a grafting copolymerization method. Aniline molecules were then bonded onto the Fe3O4 nanoparticles by electrostatic self-assembly and further polymerized to obtain uniform polyaniline/Fe3O4 (PANI/Fe3O4) nanoparticles (approximately 35 nm). Finally, monodispersed Ag/PANI/Fe3O4 nanoparticles were prepared by a...

Covalent labeling of solvent exposed amino acid residues using chemical reagents/crosslinkers followed by mass spectrometric analysis can be used to determine the solvent accessible amino acids of a protein. A variety of chemical reagents containing cleavable bonds were developed to label abundantly found lysine residues on the surface of protein. To achieve efficient separation of labeled pept...

A simple methodology for encapsulating ca. 10 nm-sized superparamagnetic Fe3O4 nanoparticles in zeolitic imidazolate frameworks (ZIF-8) crystals was developed. The corresponding Fe3O4@ZIF-8 heterostructured material exhibits bifunctional properties with both high magnetization (Fe3O4) and high thermal stability, large specific surface, and catalytic properties (ZIF-8). The Fe3O4@ZIF-8 catalyst ...

Triphenylmethane (TPM) dye is one of the most prevalent and recalcitrant water contaminants. Magnetic reduced graphene oxide (rGO) is an efficient adsorbent for organic pollutants removal. However, the performance and adsorption kinetics of magnetic rGO towards TPM have not yet been studied. In this study, a magnetic Fe3O4@rGO nano-composite, which could be easily removed from water with a simp...

Fe3O4 nanoparticles were employment as an efficient and magnetically separable Nano catalyst for the synthesis of amides via one-pot Beckmann rearrangement of ketones under solvent-free conditions. Various secondary amides were synthesized by this method in moderate to good yields. The catalyst showed high thermal stability and was recovered and reused at least five times without any considerab...

This work reports a hard self-template method to synthesize core/shell like Fe3O4@C microparticles, in which the Pd nanocrystals can be alternatively incorporated into the carbon shells. The Fe3O4@polyaniline core/shell microspheres were first synthesized as the precursor by in situ polymerization of aniline onto the surface of the Fe3O4 microspheres. In a subsequent carbonization of the precur...