0 (r sin θ + z)r dz dr dθ (b) Let T be the solid ball of radius 1 centered at (2, 0, 0). Set up, but do not evaluate, a triple integral in spherical coordinates which computes the moment of inertia of T around the z-axis. Hint: First consider the change of variables u = x − 2, v = y, w = z. Solution. After the change of variables, the sphere takes the form u+v+w = 1, and the z-axis becomes the ...

OBJECTIVE To examine the imaging-detected mechanism of reduction of structural joint damage progression by tocilizumab (TCZ) in patients with rheumatoid arthritis (RA) using MRI. METHODS In a substudy of a randomised, double-blind, phase 3b study (ACT-RAY) of biologic-naïve patients with RA who were methotrexate (MTX)-inadequate responders, 63 patients were randomised to continue MTX or recei...

INTRODUCTION HLA-B*51 and HLA-B*52 are two close human leukocyte antigen (HLA) allele groups with minor amino acid differences. However, they are associated with two different vasculitides (HLA-B*51 in Behçet's disease and HLA-B*52 in Takayasu's arteritis (TAK)) and with major clinical and immunological differences. In this study, we aimed to screen a large cohort of TAK patients from Turkey fo...

This study was conducted to determine seroprevalence of Neospora infection in cattle, sheep, horses, donkeys, and dogs in Hamedan province, Iran. Blood samples (n=2254) from the animals were collected randomly during 2009 to 2012. Sera were prepared from the collected blood samples, which were then examined for the presence of antibodies against Neospora using enzyme-linked immunosorbent assay ...

OBJECTIVE To investigate the efficacy and safety ofTelbivudine +Tenofovir combination therapy in chronic hepatitis B patients, over a period of 52 weeks, in real life clinical settings. METHODS HBeAg-positive and HBeAg-negative adult CHB patients, with hepatitis B virus (HBV) DNA > 4 log10 copies/ml and ALT 1.2 times above upper limit of normal (> 30 IU/L) were started on a combination of Tel...

Every year, 536,000 women die from pregnancyrelated causes. More than 80 percent of maternal deaths worldwide are due to five direct causes: hemorrhage, sepsis, unsafe abortion, obstructed labor and hypertensive disease of pregnancy. The latest report from the Confidential Enquiries into Maternal Deaths (UK) lists eclampsia and pre-eclampsia as the second most common cause and showed an increas...

Background: Insulin increases endothelial nitric oxide (NO) production by activating endothelial nitric oxide synthase (eNOS) through protein kinase B (Akt)-mediated phosphorylation of serine residue 1179 (p-eNOS serine 1179). Because fatty acids modulate insulin-stimulated Akt signaling cascades in smooth muscle cells, we hypothesized that fatty acids would differentially regulate endothelial ...