Benign plexiform lesion may describe a rare tumor based on morphological features. Plexiform arrangement may suggest lesions which are spindled and focally show some whorling and fascicular pattern [1]. Literature has provided a vast differential diagnosis of plexiform lesion some of which include schwannoma, fibrohistiocytic tumors, angiomyxoid tumors, fibromyxoma [25]. Plexiform neurofibroma ...

RATIONALE We are reporting the first-to our knowledge-case of duodenal Plexiform Fibromyxoma causing obscure upper gastrointestinal bleeding. PATIENT CONCERNS Plexiform fibromyxoma triggered recurrent upper gastrointestinal bleeding episodes in a 63-year-old man who remained undiagnosed, despite multiple hospitalizations, extensive diagnostic workups and surgical interventions (including gast...

We report on the case of a 40-year-old patient, with no relevant medical history, who consulted for a periungual tumor on the second finger of the left hand. The lesion, which was asymptomatic, had appeared 2 years earlier, and had shown slow, progressive growth. The physical examination showed a 1-cm diameter tumor with poorly defined borders that was not attached to the deep layers (Fig. 1A)....

Plexiform fibromyxoma is a very rare mesenchymal tumor of the stomach, found almost exclusively in the antrum/pylorus region. The most common presenting symptoms are anemia, hematemesis, nausea and unintentional weight loss, without sex or age predilection. We describe here two cases of plexiform fibromyxoma, involving a 16-year-old female and a 34-year-old male. Both patients underwent complet...

Primary pulmonary microcystic fibromyxoma is very rare. We describe a case of 68-year-old female who had a 4 months history of thorax suffocation and dyspnea. Computed tomography revealed a well-circumscribed nodule with a diameter of approximately 2.2 cm in the right upper lobe. After extensive workup, she received a right upper lobe wedge resection. Pathologically, microcystic architecture wi...

Gastric plexiform fibromyxoma (PF) is a rare mesenchymal tumor with a histologically distinctive multinodular pattern, dissimilar to conventional gastrointestinal stromal tumor (GIST). The current study presents one case of gastric PF, and one case of GIST with a platelet-derived growth factor receptor α (PDGFRA) mutation mimicking PF, and discusses their differential diagnoses. The two patient...

A case of ossifying fibromyxoid tumour of the soft part, a rare neoplasm arising about the knee of a young man is reported. The tumour has the characteristic morphology, having a thin bony shell, vascular myxohyaline stroma with oval or slightly spindly epitheloid cells arranged in cord pattern. The important histomorphological features have been highlighted and illustrated. The histogenesis, b...

Nerve sheath myxoma (NSM) is a rare benign tumour of peripheral nerves. It is seen in middle aged adults with slight female predilection and presents as a slow growing painless mass. The commonest sites are extremities, scalp, back and neck. Microscopically it has a typical morphological appearance. It is multilobulated and is composed of spindle and stellate shaped cells set in an abundant myx...