The International Atomic Energy Agency Technical Reports Series-398 code of practice for dosimetry recommends measuring photon percentage depth dose (PDD) curves with parallel-plate chambers. This code of practice was published before flattening filter-free (FFF) beams were widely used in clinical linear accelerators. The choice of detector for PDD measurements needs to be reassessed for FFF be...

A serial link transmitter fabricated in a large-scale integrated 0.4m CMOS process uses multilevel signaling (4PAM) and a three-tap pre-emphasis filter to reduce intersymbol interference (ISI) caused by channel low-pass effects. Due to the process-limited on-chip frequency, the transmitter output driver is designed as a 5 : 1 multiplexer to reduce the required clock frequency to one-fifth the s...

A highly current-efficient and fast transient response capacitor-free low-dropout regulator (LDO) for Systemon-Chip (SoC) applications is presented in this paper. The proposed architecture is implemented using 0.35 μm CMOS technology. The proposed circuit is based on differential transconductance and push-pull amplifier. Common mode feedback (CMFB) resistors and direct voltage spike detection u...

A linearly-tunable ULV transconductor featuring excellent stability of the processed signal common-mode voltage upon tuning, critical for very-low voltage applications, is presented. Its employment to the synthesis of CMOS gm-C highfrequency and voiceband filters is discussed. SPICE data describe the filter characteristics. For a 1.3V-supply, their nominal passband frequencies are 1.0MHz and 3....

Background: The presence of a wedge filter in the beam trajectory can modify the beam quality and cause some changes in the dosimetry parameters which are usually difficult to be measured directly and accurately. Material and Methods: In this study the MCNP-4C Monte Carlo code was used to simulate the 9 MV photon beam generated by a linear accelerator. Upon getting a good agreement bet...

Tetrodotoxin-resistant (TTX-R) Na(+) channels are 1,000-fold less sensitive to TTX than TTX-sensitive (TTX-S) Na(+) channels. On the other hand, TTX-R channels are much more susceptible to external Cd(2+) block than TTX-S channels. A cysteine (or serine) residue situated just next to the aspartate residue of the presumable selectivity filter "DEKA" ring of the TTX-R channel has been identified ...

Ion recombination is approximately corrected for in the Task Group 51 protocol by Pion, which is calculated by a two-voltage measurement. This measurement approach may be a poor estimate of the true recombination, particularly if Pion is large (greater than 1.05). Concern exists that Pion in high-dose-per-pulse beams, such as flattening filter free (FFF) beams, may be unacceptably high, renderi...