OBJECTIVES We describe the morphologic variability in pulmonary atresia with intact ventricular septum (PAIVS) within a population-based study. BACKGROUND An uncommon disease, PAIVS shows considerable morphologic heterogeneity. Clinical reports, based mostly on small samples of patients, may not reflect the true spectrum of pathology of this condition. We have studied the entire range of morpho...

BACKGROUND/AIMS So far, surgical and interventional therapies for muscular ventricular septal defects (mVSDs) beyond the moderator band have had their limitations. Thus, alternative therapeutic strategies should be developed. We present a new animal model for the evaluation of such strategies. METHODS In a pig model (n = 9), anterolateral thoracotomy was performed for exposure of the left ven...

Cases of drainage of the pulmonary veins into the right side of the heart have been well summarized by Brody (1942). He reported 38 cases of complete, and 68 cases of partial, drainage of the pulmonary veins into the right atrium or its tributaries. The purpose of this paper is to record a further case, and to summarize the cases not reported by Brody and those which have been reported during t...

The purpose of this study was to determine whether sectioning the cervical septum is associated with intraoperative bleeding, incompetent cervix, and secondary infertility. In this prospective observational study, fourteen women with complete septate uterus who had a history of repeated pregnancy loss and infertility were treated hysteroscopically. Preoperative history included 35 pregnanci...

OBJECTIVE To compare the incidence and prognosis of subaortic stenosis associated with a ventricular septal defect and to define the morphological basis of subaortic stenosis. DESIGN Presentation and follow up data on 202 patients with subaortic stenosis seen at the Royal Liverpool Children's Hospital between 1 January 1960 and 31 December 1991 were reviewed. Survivors were traced to assess t...

In vitro effects of bFGF on neural tube, heart, and total embryonic development were investigated in 60 rat embryos (obtained from seven pregnant females) at 9.5 days of gestation that were cultured in whole rat serum (WRS), in >30 kDa serum fractions [retenate (R)], and in R+bFGF. After 48 h culture, the embryos from each group were harvested and divided into two groups. One group was analysed...

OBJECTIVES This study sought to use echocardiography to evaluate the prevalence of muscular ventricular septal defect in neonates. BACKGROUND Ventricular septal defect is usually asymptomatic and closes spontaneously. An increase in its prevalence has been noted recently. One reason is the improved detection of small defects, especially with the increased used of echocardiography. Therefore, ...

objective a 4-month-old female with osteogenesis imperfecta (oi) type ii was admitted in picu of our center due to severe respiratory distress and fever with a diagnosis of severe pneumonia, and mechanical ventilation was initiated. due to severe hypotonia, ncv and emg were performed, and spinal muscular atrophy (sma) type i was diagnosed.