نتایج جستجو برای: muscle perfusion reserve

تعداد نتایج: 402391  

Journal: :The American journal of physiology 1999
Michel A Pontari Michael R Ruggieri

Continuous measurements were made of bladder blood flow by laser Doppler flowmetry in anesthetized dogs during bladder filling and emptying. In both mucosa and muscle, perfusion was inversely proportional to intravesical pressure. There was significantly greater perfusion in the bladder mucosa of males than females at baseline and up to 10 cm water filling pressure but not in the muscle. Intra-...

2014
Masliza Mahmod Jane M Francis Nikhil Pal Andrew Lewis Sairia Dass Ravi De Silva Mario Petrou Rana Sayeed Stephen Westaby Matthew D Robson Houman Ashrafian Stefan Neubauer Theodoros D Karamitsos

Background Left ventricular hypertrophy in aortic stenosis (AS) is characterised by reduced myocardial perfusion reserve due to coronary microvascular dysfunction. However, it remains unclear whether the hypoperfusion seen in severe AS leads to myocardial tissue deoxygenation and thus, ischemia during stress. The aim of this study was to assess myocardial oxygenation and perfusion in patients w...

2012
Shazia T Hussain Matthias Paul Sven Plein Gerry P McCann Ajay Shah Amedeo Chiribiri Geraint Morton Andreas Schuster Mark Westwood Divaka Perera Michael Marber Eike Nagel

Background Coronary angiography and the extent of coronary luminal stenosis has historically been the main factor used in guiding decisions regarding revascularisation in patients with stable coronary artery disease. More recently, revascularisation based on invasive fractional flow reserve (FFR) measurements has been shown to result in a significant benefit for event free survival. Cardiac mag...

Journal: :Journal of applied physiology 2010
Jong-Shyan Wang Min-Huan Wu Tso-Yen Mao Tieh-cheng Fu Chih-Chin Hsu

Hypoxic preconditioning prevents cerebrovascular/cardiovascular disorders by increasing resistance to acute ischemic stress, but severe hypoxic exposure disturbs vascular hemodynamics. This study compared how various exercise regimens with/without hypoxia affect hemodynamics and oxygenation in cardiac, muscle, and cerebral tissues during severe hypoxic exposure. Sixty sedentary males were rando...

2014
Yang Yang Sujith Kuruvilla Craig H Meyer Frederick H Epstein Angela M Taylor Christopher M Kramer Michael Salerno

Background Quantitative first-pass CMR can assess the severity of microvascular coronary dysfunction(MCD) in subjects with signs and symptoms of ischemia but without obstructive coronary artery disease(CAD). In patients with MCD, abnormalities of myocardial perfusion reserve (MPR) occur globally but may also vary in their transmural extent. Thus, high spatial resolution quantitative CMR perfusi...

Journal: :European heart journal 2012
Robert Manka Ingo Paetsch Sebastian Kozerke Marco Moccetti Rainer Hoffmann Joerg Schroeder Sebastian Reith Bernhard Schnackenburg Oliver Gaemperli Lukas Wissmann Christophe A Wyss Philipp A Kaufmann Roberto Corti Peter Boesiger Nikolaus Marx Thomas F Lüscher Cosima Jahnke

AIMS Dynamic three-dimensional-cardiac magnetic resonance (3D-CMR) perfusion proved highly diagnostic for the detection of angiographically defined coronary artery disease (CAD) and has been used to assess the efficacy of coronary stenting procedures. The present study aimed to relate significant coronary lesions as assessed by fractional flow reserve (FFR) to the volume of myocardial hypoenhan...

2013
Susie Parnham Suchi Grover Craig Bradbrook Govindarajan Srinivasan Carmine DePasquale Richard Woodman Jonathan Gleadle Joseph Selvanayagam

Background Cardiovascular disease is one of the commonest causes of mortality post-renal transplantation (RT), often in patients with no known cardiac disease. The cardiac phenotype in these patients is not clearly defined. Multi-parametric cardiovascular magnetic resonance (CMR) imaging enables concurrent assessment of myocardial function, perfusion and irreversible injury. We hypothesized tha...

2014
Maria Pia Donataccio Claudio Reverberi Nicola Gaibazzi

UNLABELLED A 52-year-old man presented after one episode of effort angina, normal treadmill electrocardiogram (ECG), and clearly positive adenosine cardiac magnetic resonance (aCMR) for reversible perfusion defects in the left anterior descending (LAD) coronary artery territory. Contrast high-dose dipyridamole (0.84 mg/kg per 6 min) stress echocardiography (cSE) demonstrated normal myocardial p...

2014
Dominik Buckert Volker Rasche Wolfgang Rottbauer Peter Bernhardt

Methods Eighty-six patients with intermediate risk, angina pectoris, and suspected coronary artery disease were enrolled into the study. All patients were examined in a 3 T CMR system including functional imaging of the left ventricle, adenosine and rest perfusion imaging using a bolus of 0.075 mmol/kg gadolinium based contrast agent (Dotarem, Guerbet, France), respectively. CMR studies were pe...

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