1) This study examined the ability of human subjects to match a force in their quadriceps muscle during fatigue. Twenty subjects (mean age: 23.4 yrs, mean height: 167.8 cm, mean weight, 62.6 kg) were enrolled in the experiment. In the force-matching task, the quadriceps muscle generated 50% of the MVIC (maximum voluntary isometric contraction) torque under visual control and then without visual...

Dialysis patients have severe exercise limitations related to metabolic disturbances, but muscle fatigue has not been well studied in this population. We investigated the magnitude and mechanisms of fatigue of the ankle dorsiflexor muscles in patients on maintenance hemodialysis. Thirty-three dialysis patients and twelve healthy control subjects performed incremental isometric dorsiflexion exer...

background: metabolic derangements in type 2 diabetes mellitus (t2dm) are likely to affect skeletal muscle contractile functions adversely. levo-carnitine improves muscle contractile functions in healthy humans and rats and corrects metabolic derangements in t2dm. therefore, it is likely to improve muscle contractile functions in t2dm as well. this study was designed to determine the effect of ...

Robot-assisted rehabilitation facilitates high-intensity training of the impaired upper limb in neurological rehabilitation. It has been clinically observed that persons with Multiple Sclerosis (MS) have difficulties in sustaining the training intensity during a session due to the development of activity-related muscle fatigue. An experimental observational pilot study was conducted to examine ...

Healthy untrained men performed 10 series of 12 knee eccentric extension repetitions (EE) at 160 degrees /s. The maximal voluntary isometric contraction force of the quadriceps muscle, the maximal rate of electrically induced torque development (RTD) and relaxation (RTR), isokinetic concentric torque at 30 degrees /s, the electrostimulation-induced torque at 20 and 100Hz frequencies were establ...

Sequel to spinal cord injury (SCI), functional impairment is sustained and the SCI individuals are often confined to wheelchair usage. Current trends of walking rehabilitation adopted is functional electrical stimulation (FES) assisted gait with partial body weight support. However, lack of lower limb proprioception, inability to control complex joint trajectory, rapid energy consumption, unsta...

Muscle fatigue, a reduction in force as a consequence of exercise, is an important factor for any animal that moves, and can result from both peripheral and/or central mechanisms. Although much is known about whole-limb force generation and activation patterns in fatigued muscles under sustained isometric contractions, little is known about the in vivo dynamics of limb muscle function in relati...

Fatigue is a common symptom of numerous acute and chronic diseases, including myalgic encephalomyelitis/chronic fatigue syndrome, multiple sclerosis, heart failure, cancer, and many others. In these multi-system diseases the physiological determinants of enhanced fatigue encompass a combination of metabolic, neurological, and myofibrillar adaptations. Previous research studies have focused on a...

Muscle fatigue represents a complex phenomenon encompassing various causes, mechanisms and forms of manifestation. Continuous monitoring of local muscle fatigue during performance of certain work is possible by measuring myoelectric activity of particular muscles by the method of surface electromyography. Biochemical and physiological changes in muscles during fatiguing contractions are reflect...