sjogren-larsson syndrome (sls) is an inherited autosomal recessive neurocutaneous disorder with congenital ichthyosis, spastic diplegia or quadriplegia and mental retardation. we report a case of sjogren-larsson syndrome with clinical profile (mental retardation, ichthyosis, spastic diplegia) and mri findings such as seen in multiple sclerosis (ms). so this rare syndrome can be another differen...

conclusions according to our results, the infusion of one liter normal saline will cause a statistically significant decrease only in bd, after one hour, in patients with moderate to severe iss. the changes in sbp, pr, cvp and also ph, hco3 and hb were not statistically remarkable. background the management of trauma patients is often difficult. the american college of surgeons suggests using a...

conclusions these results suggest that treadmill training and yoga practice improved ambulatory function, fatigue and mood status in the individuals with mild to moderate ms. patients and methods thirty-one ms patients, all female with mean of age of 36.75 years and expanded disability status scale scores (edss) of 1.0 to 4.0 were recruited. subjects were randomly assigned to one of the three g...

multiple sclerosis (ms) is a demyelinating neuro- inflammatory autoimmune disease of the central nervous system. genetic predisposition has long been suspected in the etiology of this disease. the association between mthfr polymorphisms and ms has been ivestigated in different ethnic groups. we investigated the association between mthfr c677t and a1298c missense variants and ms in 180 patients ...

background: hormones can play a significant role in the pathogenesis of multiple sclerosis (ms). the aim of this study was to compare levels of ghrelin, leptin, and testosterone hormones of ms patients with healthy subjects, and assess the relationship between levels of peptide hormone and sex hormones in ms patients. methods: 35 ms patients with definite relapsing remitting multiple sclerosis ...

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abstract objective: according to the previous studies, 2-5 percent of patients with multiple sclerosis experienced the first episode of disease before the age 16.  since the age of onset among children is not similar to that in general population, clinicians often fail to early diagnose the disease. this study aims to determine the epidemiological and clinical patterns of ms among iranian child...

a bstract       background:  patients with multiple sclerosis experience hospitalization several times in their lives. certainly, providing ef fi cient and high-quality care by healthcare professionals is not possible unless the experiences of patients’ hospitalization are taken into consideration. this qualitative study was aimed to identify experiences of patients with multiple sclerosis in t...

conclusions herpes simplex virus was present in more patients with ms than healthy cases. hsv may be directly or indirectly associated with ms development. further comprehensive molecular studies are needed to confirm the etiopathologic association between hsv and ms disease. results totally, 63 (76.8%) patients with ms showed a history of hsv exposure by anti-hsv testing compared to 70 (78.7%)...

conclusions the prevalence of ms showed an increasing rate of the disease in recent years. decreasing of the female to male ratio and patients’ low socio-economic level, need more studies. the increasing rate of patients with progressive relapsing feature and more disabled patients belong to this subtype show the poor prognosis. results a total of 142 patients were participated in this study. p...