melatonin has both pro-inflammatory and anti-inflammatory properties depending on the stage of inflammation. despite its therapeutic effect in alleviation of some symptoms of multiple sclerosis; the precise role of melatonin in ms pathogenesis remains a topic of debate. the aim of this study was to measure the urine level of one of melatonin products which is an index of serum melatonin level, ...

objective: multiple sclerosis (ms) is a chronic disease with prominent neurological and behavioral and psychiatric manifestations and unknown etiology which is demarcated with inflammation and destruction of white matter of brain and spinal cord and its replacement with gliotic tissue in young aged people and particularly females. the role of trace elements in multiple sclerosis is set forth in...

multiple sclerosis (ms) is an autoimmune disease that affects physical and emotional aspects of patient's lives. the aim of this study was to evaluate emotional intelligence (ei) in cases with ms.one hundred sixty six clinically definite ms and 110 healthy subjects were enrolled in this study. all participants filled valid and reliable persian version emotional quotient inventory (eq-i) questio...

multiple sclerosis (ms) is an autoimmune disease of the central nervous system associated to myelin loss and neurodegeneration. clinically patients suffer from diverse symptoms and face the risk to become wheelchair-bound. at the moment ms is incurable, thus there is an unmet need for therapeutic options.

conclusions the results of this study showed a possible association between cmv infection and ms. further experimental and epidemiological studies using case-control approaches are needed to confirm this association. results anti-cmv was positive in 65 (79.3%) and 69 (77.5%) of the ms patients and healthy subjects, respectively (p= 0.853). similarly, 23 (28%) and 2 (2.2%) patients were positive...

background: multiple sclerosis (ms), the most common demyelinating disease of the cns, is immunologically mediated in genetically susceptible individuals. receptors for the fc fragment of igg (fcγr) might induce inflammatory responses through linking the humoral and cellular immune responses by targeting immune complexes to effector cells. polymorphisms in some fcγr genes are associated with va...

We used a surface-based analysis of T2* relaxation rates at 7 T magnetic resonance imaging, which allows sampling quantitative T2* throughout the cortical width, to map in vivo the spatial distribution of intracortical pathology in multiple sclerosis. Ultra-high resolution quantitative T2* maps were obtained in 10 subjects with clinically isolated syndrome/early multiple sclerosis (≤ 3 years di...

arm grooves of star-fish have mesenchymal stem cells derived from adipose tissue cell. widespread studies have shown that stem cells derived from adipose-derived mesenchymal stem cell from bone marrow have many similarities in terms of the ability to differentiate into a variety of tissues. most of the animals live in warm and shallow waters and the waters of this feature is that it is low in d...

adult neurogenesis is a process of producing nerve cells from their progenitor that occurs in some areas in the brain such as the hypothalamus. low activity in this area plays a role in neural degeneration and diseases such as multiple sclerosis, epilepsy and depression. ms is a neurodegenerative disease with a permanent disability that the main reason for it is axonal degeneration and neuronal...

multiple sclerosis (ms) is an inflammatory disorder, in which neurons become demyelinated. to date, its etiology has remained unknown. nevertheless, certain features are inspected to provoke ms. for instance, improper function of immune cells is widely believed to be the basis of such disorder. in this concept, ms is stated as an autoimmune disease, which was asserted by major of studies, as cd...