objective(s): in order to grow cells in a three-dimensional (3d) microenvironment, self-assembling peptides, such as puramatrix, have emerged with potential to mimic the extracellular matrix. the aim of the present study was to investigate the influence of the self-assembling peptide on the morphology, survival, proliferation rate, migration potential, and differentiation of human meningioma st...

objective(s): the study objective was to assess the diagnostic performance of positron emission tomography (pet) for gliomas using the novel tracer 18f-fluciclovine (anti-[18f]facbc) and to evaluate the safety of this tracer in patients with clinically suspected gliomas.methods: anti-[18f]facbc was administered to 40 patients with clinically suspected high- or low-grade gliomas, followed by pet...

We present a case of cerebral infestation by Echinococcosis multilocularis mimicking an infiltrative primary brain tumor. A heavily calcified mass invading the midbrain enhanced in a cauliflower-like fashion with small peripheral nodules present on MR imaging. Perfusion-weighted MR imaging revealed low relative cerebral blood volume within the calcified lesion and peripheral hyperemia. Single-v...

Awake brain surgery has been approved as a safe and efficaceous operative procedure with the goal of maximal tumor resection and preservation of neurological function. This case report presents the first full awake primary brain tumor surgical procedure performed in Croatia.

Primitive neuroectodermal tumors (PNETs) arising directly from the lung are extremely rare but particularly aggressive neoplasms. Although thoracic PNET usually develops on the chest wall, there have been reports of primary Ewing sarcoma/PNET of the lung. We present the case of a 16-year-old male with PNET diagnosed following histologic and immunohistochemical examination of a videoassisted tho...

background and purpose: cancer and cerebrovascular accidents (cva) are two most common causes of mortality and morbidity in the elderly. patients with brain tumor can be highly affected by postsurgical stroke. cva may be the first manifestation in these patients . therefore, we aimed to assess the epidemiological factors affecting cva after brain surgery. methods: in this cross-sectional study ...

Abstract BACKGROUND Tumor-homing tumoricidal neural stem cell (tNSC) therapy is a promising new strategy that recently entered human patient testing for glioblastoma (GBM). Developing strategies tNSC to overcome intratumoral heterogeneity, variable cancer invasiveness, and differential drug response of GBM will be essential efficacious treatment in the clinical setting. We sought create novel h...

the presence of tumor thrombus in the right atrium is frequently the result of direct intraluminal extension of infra-diaphragmatic malignancy into the inferior vena cava (ivc) or supradiaphragmatic carcinoma into the superior vena cava (svc). right atrial tumor thrombus with extension into both svc and ivc has not been reported in the literature. we present a patient who presented with symptom...

Tumor Therapy In article number 2106606, Nan Qin, Tiger H. Tao, and co-workers report a heterogenous silk microneedle patch to spatiotemporally sequentially deliver multiple therapeutic drugs for hemostasis, anti-angiogenesis, apoptosis of brain tumor cells. Drug release kinetics are well-defined by tuning the crosslinking degree applying trigger transcranial NIR-light irradiation. This biodegr...